Atrial fibrillation (AF) is commonly associated with heart failure. A bidirectional relationship
exists between the two—AF exacerbates heart failure causing a significant increase in heart …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and its prevalence is
increasing with the ageing of the population. Presently available treatment options are far …

Atrial fibrillation (AF) is the most prevalent sustained arrhythmia. As the most important risk
factor for embolic stroke, AF is associated with a high morbidity and mortality. Despite …

Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases that often
co-exist. Animal models have suggested complex AF-promoting atrial structural, electrical …

Atrial fibrillation (AF) is the most frequently encountered clinical arrhythmia and is associated
with increased morbidity and mortality. Ectopic activity and reentry are considered major …

Atrial electrical and structural alterations (remodeling) have emerged as key elements in the
development of the atrial fibrillation (AF) substrate. Evidence points to abnormalities in …

Background—Despite adequate rate control, the combination of atrial fibrillation with heart
failure (HF) has been shown, in a number of studies, to hasten HF progression. In this …

Despite considerable basic research into the mechanisms of atrial fibrillation (AF), not much
progress has been made in the prognosis of patients with AF. With the exception of …

Aims Ageing-related cardiac disorders such as heart failure and atrial fibrillation often
present with intracellular calcium homeostasis dysfunction. However, knowledge of the …

did not show an increase in Ca2+ sparks or DADs, suggesting the requirement of ox-CaMKII
in AngII-induced SR Ca2+ leak and DADs. Finally, they demonstrated that the proarrhythmic …