Alpha-lipoic acid in ovarian vitrification solution for in vitro culture or autotransplantation as future strategies for the restoration of ovarian function in sheep

LVS Ñaupas, DCC Brito, SS Souza, FAS Brandão… - Livestock Science, 2022 - Elsevier
Vitrification is a promising method for ovarian cortex preservation, however, oxidative stress
resulting from excessive free radical production can cause irreversible damage to the ovary …

Alpha lipoic acid supplementation improves ovarian tissue vitrification outcome: an alternative to preserve the ovarian function of Morada Nova Ewe

LVS Ñaupas, DCC Brito, SS de Souza… - Reproductive …, 2021 - Springer
This study evaluated the effect of adding alpha lipoic acid (ALA) to the vitrification solution of
sheep ovarian tissue on 7 days of in vitro culture or 15 days of xenotransplantion. ALA was …

Alpha lipoic acid controls degeneration and ensures follicular development in ovine ovarian tissue cultured in vitro

LVS Ñaupas, FDR Gomes, ACA Ferreira, SM Morais… - Theriogenology, 2024 - Elsevier
This study aims to evaluate the effects of adding alpha lipoic acid (ALA) to the in vitro
ovarian tissue culture medium, either fresh or after vitrification/warming. For this purpose, 10 …

Effect of catalase or alpha lipoic acid supplementation in the vitrification solution of ovine ovarian tissue

LM Silva, GT Mbemya, DD Guerreiro… - Biopreservation and …, 2018 - liebertpub.com
Aim: The present study evaluates the effect of different concentrations of antioxidants
(catalase-CAT and alpha lipoic acid-ALA) on the follicular activation and morphology, DNA …

Natural antioxidants in the vitrification solution improve the ovine ovarian tissue preservation

MLG dos Santos Morais, DCC de Brito, Y Pinto… - Reproductive …, 2019 - Elsevier
The present study evaluated the effect of the addition of antioxidants anethole (AN) and
robinin (RO) in the vitrification solution, and the in vitro incubation (IVI) medium of ovine …

Effect of various antioxidants on ovarian tissue vitrification success in sheep

AA Malik, KA Sofi, B Qureshi, AH Akand, SA Shah… - …, 2024 - ingentaconnect.com
BACKGROUND: Vitrification is a technique of cryopreservation that has been proposed as a
promising alternative method for the preservation of oocytes, embryos and gonadal tissue …

[HTML][HTML] How origin of ovaries influences the vitrification outcome of bovine ovarian tissue: effects of side of ovaries and corpus luteum

MH Shahsavari, G Moghaddam, KA Alves… - Veterinary Research …, 2023 - ncbi.nlm.nih.gov
Although cryopreservation of ovarian tissue has advanced greatly, it remains a challenge,
and protocols should be optimized to handle the heterogeneous nature of ovarian samples …

Alpha-lipoic acid improves bovine preimplantation blastocyst quality and cryotolerance

MC Fabra, JP Anchordoquy, AC Carranza-Martín… - Theriogenology, 2023 - Elsevier
In vitro embryo production has grown in recent decades due to its great potential for cattle
production. However, the quality of in vitro-produced embryos is lower compared with those …

Appropriate osmotic balance duration for different volumes of ovarian tissue in vitrification solution: a study of ovary tissue vitrification and transplantation in sheep

D Ling, Z Xiaomin, C Qing, Y Yanzhou… - …, 2016 - ingentaconnect.com
BACKGROUND: Auto-transplantation of cryopreserved ovarian tissue has become a
promising method for fertility preservation and standardization of the process is crucial for …

[PDF][PDF] The influence of alpha-lipoic acid on ovarian follicle growth in induced aging mice

IB Sharum, EO Hussien, F Tawfeeq - Iraqi Journal of Veterinary Sciences, 2023 - iasj.net
The ovary contains follicles at various developmental stages. The present study aimed to
investigate the antioxidant efficiency of alpha-lipoic acid (α-LA) on follicle growth in induced …