[HTML][HTML] Transcriptomic cell type structures in vivo neuronal activity across multiple timescales
Cell type is hypothesized to be a key determinant of a neuron's role within a circuit. Here, we
examine whether a neuron's transcriptomic type influences the timing of its activity. We …
examine whether a neuron's transcriptomic type influences the timing of its activity. We …
Learning time-invariant representations for individual neurons from population dynamics
Neurons can display highly variable dynamics. While such variability presumably supports
the wide range of behaviors generated by the organism, their gene expressions are …
the wide range of behaviors generated by the organism, their gene expressions are …
[HTML][HTML] Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types
Which cell types constitute brain circuits is a fundamental question, but establishing the
correspondence across cellular data modalities is challenging. Bio-realistic models allow …
correspondence across cellular data modalities is challenging. Bio-realistic models allow …
A coupled autoencoder approach for multi-modal analysis of cell types
Recent developments in high throughput profiling of individual neurons have spurred data
driven exploration of the idea that there exist natural groupings of neurons referred to as cell …
driven exploration of the idea that there exist natural groupings of neurons referred to as cell …
[HTML][HTML] A diversity of intrinsic timescales underlie neural computations
SE Cavanagh, LT Hunt, SW Kennerley - Frontiers in Neural Circuits, 2020 - frontiersin.org
Neural processing occurs across a range of temporal scales. To facilitate this, the brain uses
fast-changing representations reflecting momentary sensory input alongside more …
fast-changing representations reflecting momentary sensory input alongside more …
[HTML][HTML] Transcriptomic correlates of electrophysiological and morphological diversity within and across excitatory and inhibitory neuron classes
C Bomkamp, SJ Tripathy… - PLoS computational …, 2019 - journals.plos.org
In order to further our understanding of how gene expression contributes to key functional
properties of neurons, we combined publicly accessible gene expression, electrophysiology …
properties of neurons, we combined publicly accessible gene expression, electrophysiology …
[HTML][HTML] Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex
The brain consists of many cell classes yet in vivo electrophysiology recordings are typically
unable to identify and monitor their activity in the behaving animal. Here, we employed a …
unable to identify and monitor their activity in the behaving animal. Here, we employed a …
[HTML][HTML] Ancestral circuits for the coordinated modulation of brain state
Internal states of the brain profoundly influence behavior. Fluctuating states such as
alertness can be governed by neuromodulation, but the underlying mechanisms and cell …
alertness can be governed by neuromodulation, but the underlying mechanisms and cell …
Cortical pyramidal and parvalbumin cells exhibit distinct spatiotemporal extracellular electric potentials
LJ Sukman, E Stark - Eneuro, 2022 - eneuro.org
Brain circuits are composed of diverse cell types with distinct morphologies, connections,
and distributions of ion channels. Modeling suggests that the spatial distribution of the …
and distributions of ion channels. Modeling suggests that the spatial distribution of the …
[HTML][HTML] A deep-learning strategy to identify cell types across species from high-density extracellular recordings
M Beau, DJ Herzfeld, F Naveros, ME Hemelt… - bioRxiv, 2024 - ncbi.nlm.nih.gov
High-density probes allow electrophysiological recordings from many neurons
simultaneously across entire brain circuits but don't reveal cell type. Here, we develop a …
simultaneously across entire brain circuits but don't reveal cell type. Here, we develop a …