Background Previous catheter-based renal denervation studies have reported variable
efficacy results. We aimed to evaluate safety and blood pressure response after renal …

Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …

Background Renal denervation has been shown to lower blood pressure in the presence of
antihypertensive medications; however, long-term safety and efficacy data from randomised …

Background Catheter-based renal denervation has significantly reduced blood pressure in
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL …

Objectives The authors performed an updated meta-analysis of randomized placebo-
controlled trials of renal denervation and specifically compared the effect of renal …

Summary Background The SYMPLICITY HTN-3 (Renal Denervation in Patients With
Uncontrolled Hypertension) trial showed the safety but not efficacy of the Symplicity system …

Background: The DENERHTN trial (Renal Denervation for Hypertension) confirmed the
blood pressure–lowering efficacy of renal denervation added to a standardized stepped …

The efficacy of renal denervation has been controversial, but recent randomized sham-
controlled trials demonstrated significant blood pressure reductions after renal denervation …

Background Renal denervation (RDN) reduces blood pressure (BP) in patients with
uncontrolled hypertension in the absence of antihypertensive medications. Objectives This …

Aim The aim of this study was to determine long-term results of renal artery denervation for
treatment of treatment-resistant hypertension in the SYMPLICITY HTN-2 study. Methods …