Peptide receptor radionuclide therapy

J Hofland, T Brabander, FA Verburg… - The Journal of …, 2022 - academic.oup.com
The concept of using a targeting molecule labeled with a diagnostic radionuclide for using
positron emission tomography or single photon emission computed tomography imaging …

[HTML][HTML] Peptide receptor radionuclide therapy (PRRT): innovations and improvements

E Merola, CM Grana - Cancers, 2023 - mdpi.com
Simple Summary This article discusses the use of peptide receptor radionuclide therapy
(PRRT) as a key treatment method for advanced, unresectable neuroendocrine tumors. It …

[HTML][HTML] Peptide receptor radionuclide therapy using radiolabeled somatostatin analogs: focus on future developments

SM Bison, MW Konijnenberg, M Melis, SE Pool… - Clinical and translational …, 2014 - Springer
Peptide receptor radionuclide therapy (PRRT) has been shown to be an effective treatment
for neuroendocrine tumors (NETs) if curative surgery is not an option. A majority of NETs …

Peptide receptor radionuclide therapy for advanced gastroenteropancreatic neuroendocrine tumors—from oncology perspective

A Kolasińska-Ćwikła, A Łowczak… - Nuclear Medicine …, 2018 - journals.viamedica.pl
Abstract Peptide Receptor Radionuclide Therapy (PRRT) is a form of molecular targeted
therapy which is performed by using a small peptide (somatostatin analogue—SSA) that is …

Update: Improvement Strategies for Peptide Receptor Scintigraphy and Radionuclide Therapy

M de Visser, SM Verwijnen… - Cancer biotherapy & …, 2008 - liebertpub.com
Somatostatin receptor-targeting peptides are widely used for the imaging and therapy of
neuroendocrine tumors. Peptide-receptor radionuclide therapy (PRRT) in neuroendocrine …

Somatostatin receptor 2–targeting compounds

DAS Duijzentkunst, DJ Kwekkeboom… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The molecular imaging and treatment of neuroendocrine tumors (NETs) with radiolabeled
somatostatin analogs represent a milestone in the development of theranostic compounds …

Somatostatin receptor-targeted radionuclide therapy in patients with gastroenteropancreatic neuroendocrine tumors

DJ Kwekkeboom, WW de Herder… - Endocrinology and …, 2011 - endo.theclinics.com
Peptide receptor scintigraphy in humans started with the in vivo demonstration of
somatostatin receptor-positive tumors in patients using a radioiodinated somatostatin …

Evaluating the role of theranostics in grade 3 neuroendocrine neoplasms

N Waseem, CM Aparici, PL Kunz - Journal of Nuclear Medicine, 2019 - Soc Nuclear Med
The diagnosis and subsequent therapy of neuroendocrine neoplasms (NENs) have long
relied on somatostatin receptor (SSTR) expression. The field of theranostics now uses …

Peptides and receptors in image-guided therapy: theranostics for neuroendocrine neoplasms

RP Baum, HR Kulkarni, C Carreras - Seminars in nuclear medicine, 2012 - Elsevier
Theranostics of neuroendocrine neoplasms (NENs) based on molecular imaging using
receptor positron emission tomography/computed tomography (PET/CT) with 68Ga-labeled …

Peptide receptor radionuclide therapy in grade 3 neuroendocrine neoplasms: safety and survival analysis in 69 patients

J Zhang, HR Kulkarni, A Singh, K Niepsch… - Journal of Nuclear …, 2019 - Soc Nuclear Med
To date, limited data are available concerning peptide receptor radionuclide therapy (PRRT)
of grade 3 (G3) neuroendocrine neoplasms (NENs) with a Ki-67 proliferation index of …