Retinoic Acid Treatment Mitigates PM2. 5-Induced Type 2 Inflammation: Insights into Modulation of Innate Immune Responses

HJ Lee, DK Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
Some studies have demonstrated the effects of particulate matter (PM) on chronic
rhinosinusitis with nasal polyps (CRSwNP) development, as well as the therapeutic role of …

[HTML][HTML] Effect of airborne particulate matter on the immunologic characteristics of chronic rhinosinusitis with nasal polyps

HJ Lee, DK Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
The inflammatory mechanisms of environmental pollutants in chronic rhinosinusitis (CRS)
have recently been proposed. However, the mechanisms underlying the inflammatory …

[HTML][HTML] PM2.5 Exacerbates Oxidative Stress and Inflammatory Response through the Nrf2/NF-κB Signaling Pathway in OVA-Induced Allergic Rhinitis Mouse Model

CH Piao, Y Fan, TV Nguyen, HS Shin, HT Kim… - International Journal of …, 2021 - mdpi.com
Air pollution-related particulate matter (PM) exposure reportedly enhances allergic airway
inflammation. Some studies have shown an association between PM exposure and a risk for …

PM2. 5 exposure regulates Th1/Th2/Th17 cytokine production through NF-κB signaling in combined allergic rhinitis and asthma syndrome

CH Piao, Y Fan, T Van Nguyen, CH Song… - International …, 2023 - Elsevier
Background Particulate matter (PM) is a major component of air pollution from emissions
from anthropogenic and natural sources and is a serious problem worldwide due to its …

[HTML][HTML] Fine particulate matter exposure exacerbated nasal mucosal damage in allergic rhinitis mice via NLRP3 mediated pyroptosis

J Li, Y Zhang, L Zhang, Z An, J Song, C Wang… - Ecotoxicology and …, 2021 - Elsevier
Background The incidence of nasal allergy/allergic rhinitis (AR) is rising worldwide, which
has become a serious public health problem. Epidemiological studies point that exposure to …

Effect of PM2. 5 on MicroRNA expression and function in nasal mucosa of rats with allergic rhinitis

Y Huang, ZQ Guo, RX Zhang… - American Journal of …, 2020 - journals.sagepub.com
Background Particulate matter 2.5 (PM2. 5) refers to particulate matter with aerodynamic
equivalent diameter less than or equal to 2.5 µm, which is an important component of air …

Airborne fine particulate matter induces oxidative stress and inflammation in human nasal epithelial cells

Z Hong, Z Guo, R Zhang, J Xu, W Dong… - The Tohoku journal of …, 2016 - jstage.jst.go.jp
Airborne fine particulate matter with an aerodynamic diameter equal to or smaller than 2.5
μm is abbreviated as PM 2.5, which is one of the main components in air pollution. Exposure …

[HTML][HTML] Nuclear factor κB/microRNA-155 upregulates the expression pattern of cytokines in regulating the relapse of chronic sinusitis with nasal polyps and the …

J Du, H Lv, X Dou, Z Cao - Medical Science Monitor: International …, 2020 - ncbi.nlm.nih.gov
Background The aim of this study was to explore the upregulated nuclear factor κB (NF-
κB)/microRNA-155 (miR-155) in regulating inflammatory responses and relapse of chronic …

Local IL-17 positive T cells are functionally associated with neutrophil infiltration and their development is regulated by mucosal microenvironment in nasal polyps

S Yu, C Cao, Q Li, X Wen, X Guo, Q Bao, Y Zhou… - Inflammation …, 2021 - Springer
Objective and design IL-17 plays essential roles in neutrophilic inflammation in the lower
respiratory tract, however, the characteristics of local IL-17+ T cells in nasal inflammatory …

[HTML][HTML] Tc17/IL-17A up-regulated the expression of MMP-9 via NF-κB pathway in nasal epithelial cells of patients with chronic rhinosinusitis

X Chen, L Chang, X Li, J Huang, L Yang, X Lai… - Frontiers in …, 2018 - frontiersin.org
Chronic rhinosinusitis (CRS) is a common chronic inflammatory disease of the upper
airways involving nasal cavity and sinus. Deriving both from its clinical complexity with …