Zebrafish as a Model to Study Retinoic Acid Signaling in Development and Disease
MR Hawkins, RA Wingert - Biomedicines, 2023 - mdpi.com
Retinoic acid (RA) is a metabolite of vitamin A (retinol) that plays various roles in
development to influence differentiation, patterning, and organogenesis. RA also serves as …
development to influence differentiation, patterning, and organogenesis. RA also serves as …
Retinoic acid signaling pathways
NB Ghyselinck, G Duester - Development, 2019 - journals.biologists.com
Retinoic acid (RA), a metabolite of retinol (vitamin A), functions as a ligand for nuclear RA
receptors (RARs) that regulate development of chordate animals. RA-RARs can activate or …
receptors (RARs) that regulate development of chordate animals. RA-RARs can activate or …
Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors
JS Waxman, D Yelon - … dynamics: an official publication of the …, 2007 - Wiley Online Library
Retinoic acid (RA) signaling is important for multiple aspects of embryonic development and
tissue homeostasis. Heterodimers of retinoic acid receptors (RARs) and retinoid X receptors …
tissue homeostasis. Heterodimers of retinoic acid receptors (RARs) and retinoid X receptors …
Retinoic acid, RARs and early development
M Berenguer, G Duester - Journal of molecular …, 2022 - jme.bioscientifica.com
Vitamin A (retinol) is an important nutrient for embryonic development and adult health. Early
studies identified retinoic acid (RA) as a metabolite of retinol, however, its importance was …
studies identified retinoic acid (RA) as a metabolite of retinol, however, its importance was …
Transgenic retinoic acid sensor lines in zebrafish indicate regions of available embryonic retinoic acid
A Mandal, A Rydeen, J Anderson… - Developmental …, 2013 - Wiley Online Library
Background: Retinoic acid (RA) signaling plays a critical role in vertebrate development.
Transcriptional reporters of RA signaling in zebrafish, thus far, have not reflected the broader …
Transcriptional reporters of RA signaling in zebrafish, thus far, have not reflected the broader …
Multi-species transcriptome meta-analysis of the response to retinoic acid in vertebrates and comparative analysis of the effects of retinol and retinoic acid on gene …
C Falker-Gieske, A Mott, S Franzenburg, J Tetens - BMC genomics, 2021 - Springer
Background Retinol (RO) and its active metabolite retinoic acid (RA) are major regulators of
gene expression in vertebrates and influence various processes like organ development …
gene expression in vertebrates and influence various processes like organ development …
From carrot to clinic: an overview of the retinoic acid signaling pathway
M Theodosiou, V Laudet, M Schubert - Cellular and molecular life sciences, 2010 - Springer
Vitamin A is essential for the formation and maintenance of many body tissues. It is also
important for embryonic growth and development and can act as a teratogen at critical …
important for embryonic growth and development and can act as a teratogen at critical …
New insights into the control of cell fate choices and differentiation by retinoic acid in cranial, axial and caudal structures
H Draut, T Liebenstein, G Begemann - Biomolecules, 2019 - mdpi.com
Retinoic acid (RA) signaling is an important regulator of chordate development. RA binds to
nuclear RA receptors that control the transcriptional activity of target genes. Controlled local …
nuclear RA receptors that control the transcriptional activity of target genes. Controlled local …
[HTML][HTML] Combinatorial roles for zebrafish retinoic acid receptors in the hindbrain, limbs and pharyngeal arches
A Linville, K Radtke, JS Waxman, D Yelon… - Developmental …, 2009 - Elsevier
Retinoic acid (RA) signaling regulates multiple aspects of vertebrate embryonic
development and tissue patterning, in part through the local availability of nuclear hormone …
development and tissue patterning, in part through the local availability of nuclear hormone …
A conserved role for retinoid signaling in vertebrate pancreas development
D Stafford, A Hornbruch, PR Mueller… - Development genes and …, 2004 - Springer
Retinoic acid (RA) signaling plays critical roles in the regionalization of the central nervous
system and mesoderm of all vertebrates that have been examined. However, to date, a role …
system and mesoderm of all vertebrates that have been examined. However, to date, a role …