The nuclear factor-κB (NF-κB)/REL family of transcription factors has a central role in
coordinating the expression of a wide variety of genes that control immune responses. There …

Research on the biological function of nuclear factor-κB (NF-κB), a key mediator of inducible
transcription in the immune system, has traditionally focused on its role in the initiation of …

The mammalian Rel/NF-κB family of transcription factors, including RelA, c-Rel, RelB, NF-
κB1 (p50 and its precursor p105), and NF-κB2 (p52 and its precursor p100), plays a central …

NF-κB was first discovered and characterized 25 years ago as a key regulator of inducible
gene expression in the immune system. Thus, it is not surprising that the clearest biological …

The NF-κB transcription factor was discovered 30 years ago and has since emerged as the
master regulator of inflammation and immune homeostasis. It achieves this status by means …

One of the primary physiological roles of nuclear factor-kappa B (NF-κB) is in the immune
system. In particular, NF-κB family members control the transcription of cytokines and …

In the 20 years since its discovery, research into the NF-κB (nuclear factor-κB) family of
transcription factors has revealed an amazing diversity of functions. NF-κB proteins are …

In the 25 years since its discovery, the nuclear factor-κB (NF-κB) family of transcription
factors has been the subject of intensive research in virtually all areas of biomedical science …

The members of the Rel/NF-κB family of transcription factors form one of the first lines of
defense against infectious diseases and cellular stress. These proteins initiate a highly …

The nuclear factor-κB (NF-κB) family of transcription factors is activated by canonical and
non-canonical signalling pathways, which differ in both signalling components and …