[HTML][HTML] Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy

S Yamagishi, T Imaizumi - Current pharmaceutical design, 2005 - ingentaconnect.com
Diabetic vascular complication is a leading cause of end-stage renal failure, acquired
blindness, a variety of neuropathies and accelerated atherosclerosis, which could account …

[HTML][HTML] Micro-and macrovascular complications in diabetes mellitus: preclinical and clinical studies

ÉB Rangel, CO Rodrigues, JR De Sa - Journal of Diabetes …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a worldwide public health problem that affects millions of people
from all age, gender, and racial and ethnic groups. DM is the leading cause of blindness and …

Molecular targets of diabetic cardiovascular complications

FK Ahmad, Z He, GL King - Current drug targets, 2005 - ingentaconnect.com
Both the macro-and microvascular complications adversely affect the life quality of patients
with diabetes and have been the leading cause of mortality and morbidity in this population …

Interactions between microvascular and macrovascular disease in diabetes: pathophysiology and therapeutic implications

AJ Krentz, G Clough, CD Byrne - Diabetes, Obesity and …, 2007 - Wiley Online Library
Convention partitions the complications of diabetes into two main subtypes. First are the
diabetes‐specific microvascular complications of retinopathy, nephropathy and neuropathy; …

Diabetic macroangiopathy: Pathogenetic insights and novel therapeutic approaches with focus on high glucose-mediated vascular damage

R Madonna, D Pieragostino, CR Balistreri, C Rossi… - Vascular …, 2018 - Elsevier
Diabetic macroangiopathy–a specific form of accelerated atherosclerosis–is characterized
by intra-plaque new vessel formation due to excessive/abnormal neovasculogenesis and …

Molecular complexities underlying the vascular complications of diabetes mellitus–A comprehensive review

S Paul, A Ali, R Katare - Journal of Diabetes and its Complications, 2020 - Elsevier
Diabetes is a chronic disease, characterized by hyperglycemia, which refers to the elevated
levels of glucose in the blood, due to the inability of the body to produce or use insulin …

The pathologic continuum of diabetic vascular disease

G Orasanu, J Plutzky - Journal of the American College of Cardiology, 2009 - jacc.org
Hyperglycemia can promote vascular complications by multiple mechanisms, with formation
of advanced glycation end products and increased oxidative stress proposed to contribute to …

Diabetes‐associated macrovasculopathy: pathophysiology and pathogenesis

S Rahman, T Rahman, AAS Ismail… - Diabetes, Obesity and …, 2007 - Wiley Online Library
The complications associated with diabetic vasculopathy are commonly grouped into two
categories: microvascular and macrovascular complications. In diabetes, macrovascular …

The pathobiology of diabetic vascular complications—cardiovascular and kidney disease

SP Gray, K Jandeleit-Dahm - Journal of molecular medicine, 2014 - Springer
With the increasing incidence of obesity and type 2 diabetes, it is predicted that more than
half of Americans will have diabetes or pre-diabetes by 2020. Diabetic patients develop …