Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …

Abstract microbeMASST, a taxonomically informed mass spectrometry (MS) search tool,
tackles limited microbial metabolite annotation in untargeted metabolomics experiments …

Microbial metabolomics focuses on the analysis of intracellular or extracellular primary
metabolites, signaling molecules, hormones, and secondary metabolites, and it is an …

Metabolomics is an omics technique aiming at qualitatively and quantitatively describing a
metabolome by various analytical platforms. It is an indispensable component of modern …

Highlights•Microbiome-associated metabolite pools aid discovery of novel functions.•Guilt-
by-association approaches identify microbial derivatives of standard metabolites.•Machine …

Metabolomics is the comprehensive (qualitative and quantitative) analysis of all metabolites
within an organism or a biological system. By studying endogenous metabolites produced …

Achieving metabolome data with satisfactory coverage is a formidable challenge in
metabolomics because metabolites are a chemically highly diverse group of compounds …

Highlights•Mass spectrometry techniques are powerful tools in studying specialized
metabolites production from microbial colonies.•Direct analysis of microbial colonies can be …

Along with genes and proteins, metabolites play important roles in sustaining life. Their
functions include “primary” functions in metabolism and energy storage, as well as …

Covering: 2000 to 2016 The labor-intensive process of microbial natural product discovery is
contingent upon identifying discrete secondary metabolites of interest within complex …