Physiological mechanisms inherent to diabetes involved in the development of dementia: Alzheimer's disease

H Mohamed-Mohamed, V García-Morales… - Neurology …, 2023 - mdpi.com
Type 2 diabetes mellitus (T2D) is a metabolic disease reaching pandemic levels worldwide.
In parallel, Alzheimer's disease (AD) and vascular dementia (VaD) are the two leading …

Type 2 diabetes mellitus easily develops into Alzheimer's disease via hyperglycemia and insulin resistance

T Li, H Cao, D Ke - Current Medical Science, 2021 - Springer
With the acceleration of population aging, the incidence of type 2 diabetes mellitus (T2DM)
and Alzheimer's disease (AD) is progressively increasing due to the age-relatedness of …

An update on type 2 diabetes mellitus as a risk factor for dementia

W Li, E Huang - Journal of Alzheimer's Disease, 2016 - content.iospress.com
With the rapidly expanding evidence on brain structural and functional changes in type 2
diabetes mellitus (T2DM) patients, there is an increasing need to update our understanding …

The role of type 2 diabetes mellitus as a risk factor for Alzheimer's and Parkinson's diseases

KMA Rocha, A da Silva Goulart, MT Costa… - Research, Society and …, 2021 - rsdjournal.org
Currently, one of the most significant health problems is the increased incidence of obesity
and type 2 Diabetes mellitus (DM2). The most recent epidemiological and clinical research …

Biological mechanisms linking Alzheimer's disease and type-2 diabetes mellitus

G Mushtaq, JA Khan, MA Kamal - CNS & Neurological …, 2014 - ingentaconnect.com
The emerging data suggest that type 2 diabetes mellitus (T2DM) can contribute significantly
to the onset or progression of Alzheimer's disease (AD) either directly or as a cofactor …

Diabetes mellitus: a path to amnesia, personality, and behavior change

R Ahmad, K Chowdhury, S Kumar, M Irfan, GS Reddy… - Biology, 2022 - mdpi.com
Simple Summary Diabetes Mellitus (DM) is a metabolic disorder resulting from a disturbance
of insulin secretion, action, or both. Hyperglycemia and overproduction of superoxide induce …

Alzheimer's disease as type 3 diabetes: common pathophysiological mechanisms between Alzheimer's disease and type 2 diabetes

M Michailidis, D Moraitou, DA Tata, K Kalinderi… - International journal of …, 2022 - mdpi.com
Globally, the incidence of type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD)
epidemics is increasing rapidly and has huge financial and emotional costs. The purpose of …

Dementia in diabetes mellitus and atherosclerosis: two interrelated systemic diseases

P Mohseni-Moghaddam, R Ghobadian… - Brain research …, 2022 - Elsevier
Dementia is a common problem among the elderly and is defined by the reduction in
memory and cognition. Dementia is often caused by a neurodegenerative disease such as …

Pathophysiological mechanisms linking type 2 diabetes and dementia: review of evidence from clinical, translational and epidemiological research

OY Bello-Chavolla, NE Antonio-Villa… - Current diabetes …, 2019 - ingentaconnect.com
Background: Type 2 diabetes represents an increasing health burden world-wide and its
prevalence in particularly higher in elderly population. Consistent epidemiological evidence …

The diabetic brain and cognition

P Riederer, AD Korczyn, SS Ali, O Bajenaru… - Journal of neural …, 2017 - Springer
The prevalence of both Alzheimer's disease (AD) and vascular dementia (VaD) is increasing
with the aging of the population. Studies from the last several years have shown that people …