Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties

F Teulé, YG Miao, BH Sohn, YS Kim… - Proceedings of the …, 2012 - National Acad Sciences
The development of a spider silk-manufacturing process is of great interest. However, there
are serious problems with natural manufacturing through spider farming, and standard …

Development of a process for the spinning of synthetic spider silk

CG Copeland, BE Bell, CD Christensen… - … biomaterials science & …, 2015 - ACS Publications
Spider silks have unique mechanical properties but current efforts to duplicate those
properties with recombinant proteins have been unsuccessful. This study was designed to …

Recombinant DNA production of spider silk proteins

O Tokareva, VA Michalczechen‐Lacerda… - Microbial …, 2013 - Wiley Online Library
Spider dragline silk is considered to be the toughest biopolymer on Earth due to an
extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and …

Blueprint for a high-performance biomaterial: full-length spider dragline silk genes

NA Ayoub, JE Garb, RM Tinghitella, MA Collin… - PloS one, 2007 - journals.plos.org
Spider dragline (major ampullate) silk outperforms virtually all other natural and manmade
materials in terms of tensile strength and toughness. For this reason, the mass-production of …

High-strength and ultra-tough whole spider silk fibers spun from transgenic silkworms

J Mi, Y Zhou, S Ma, X Zhou, S Xu, Y Yang, Y Sun, Q Xia… - Matter, 2023 - cell.com
To advance ecological civilization, developing sustainable, eco-friendly high-strength and
ultra-tough alternatives to non-sustainable synthetic fibers, such as nylon, is crucial. This …

Engineered spider silk proteins for biomimetic spinning of fibers with toughness equal to dragline silks

T Arndt, G Greco, B Schmuck, J Bunz… - Advanced functional …, 2022 - Wiley Online Library
Spider silk is the toughest fiber found in nature, and bulk production of artificial spider silk
that matches its mechanical properties remains elusive. Development of miniature spider …

Strategies for making high‐performance artificial spider silk fibers

B Schmuck, G Greco, TB Pessatti… - Advanced Functional …, 2023 - Wiley Online Library
Artificial spider silk is an attractive material for many technical applications since it is a
biobased fiber that can be produced under ambient conditions but still outcompetes …

To spin or not to spin: spider silk fibers and more

E Doblhofer, A Heidebrecht, T Scheibel - Applied microbiology and …, 2015 - Springer
Spider silk fibers have a sophisticated hierarchical structure composed of proteins with
highly repetitive sequences. Their extraordinary mechanical properties, defined by a unique …

Spider silks and their applications

JA Kluge, O Rabotyagova, GG Leisk, DL Kaplan - Trends in biotechnology, 2008 - cell.com
Spider silks are characterized by remarkable diversity in their chemistry, structure and
functions, ranging from orb web construction to adhesives and cocoons. These unique …

Recombinant spider silks—biopolymers with potential for future applications

M Humenik, AM Smith, T Scheibel - Polymers, 2011 - mdpi.com
Nature has evolved a range of materials that compete with man-made materials in physical
properties; one of these is spider silk. Silk is a fibrous material that exhibits extremely high …