Origin of the nonlinear structural and mechanical properties in oppositely curved lipid mixtures

S Gupta, J Soni, A Kumar, T Mandal - The Journal of Chemical Physics, 2023 - pubs.aip.org
Structural and mechanical properties of membranes such as thickness, tail order, bending
modulus and curvature energetics play crucial role in controlling various cellular functions …

Curvature and Lipid Packing Modulate the Elastic Properties of Lipid Assemblies: Comparing HII and Lamellar Phases

N Johner, D Harries, G Khelashvili - The journal of physical …, 2014 - ACS Publications
Accumulating evidence indicates that membrane reshaping and fusion processes, as well
as regulation of membrane protein function, depend on lipid composition. Although it is …

[HTML][HTML] Molecular mechanisms of spontaneous curvature and softening in complex lipid bilayer mixtures

HJ Lessen, KC Sapp, AH Beaven, R Ashkar, AJ Sodt - Biophysical Journal, 2022 - cell.com
Membrane reshaping is an essential biological process. The chemical composition of lipid
membranes determines their mechanical properties and thus the energetics of their shape …

[HTML][HTML] Lipids with bulky head groups generate large membrane curvatures by small compositional asymmetries

A Sreekumari, R Lipowsky - The Journal of chemical physics, 2018 - pubs.aip.org
Glycolipids such as GM1 have bulky head groups consisting of several monosaccharides.
When these lipids are added to phospholipid bilayers, they generate large membrane …

[HTML][HTML] Spontaneous curvature, differential stress, and bending modulus of asymmetric lipid membranes

A Hossein, M Deserno - Biophysical Journal, 2020 - cell.com
Lipid bilayers can exhibit asymmetric states, in which the physical characteristics of one
leaflet differ from those of the other. This most visibly manifests in a different lipid …

Nano-scale “sticky tape” stabilizes open-edge boundary conditions in MD simulations of asymmetric membranes

SL Foley, M Deserno - Biophysical Journal, 2023 - cell.com
Recent advances in membrane biophysics have driven deeper investigations into lipid
bilayer asymmetry and its biological implications. Molecular dynamics simulations of …

[HTML][HTML] Nanoscale bending dynamics in mixed-chain lipid membranes

EG Kelley, MPK Frewein, O Czakkel, M Nagao - Symmetry, 2023 - mdpi.com
Lipids that have two tails of different lengths are found throughout biomembranes in nature,
yet the effects of this asymmetry on the membrane properties are not well understood …

Softening in two-component lipid mixtures by spontaneous curvature variance

A Hossein, AH Beaven, K Sapp… - The Journal of Physical …, 2024 - ACS Publications
The bending modulus of a lipid bilayer quantifies its mechanical resistance to curvature. It is
typically understood in terms of thickness; eg, thicker bilayers are usually stiffer. Here, we …

Scaling relationships for the elastic moduli and viscosity of mixed lipid membranes

EG Kelley, PD Butler, R Ashkar… - Proceedings of the …, 2020 - National Acad Sciences
The elastic and viscous properties of biological membranes play a vital role in controlling
cell functions that require local reorganization of the membrane components as well as …

Reduced apparent bending modulus in lipid membranes induced by diversity in curvature preference

A Hossein, AH Beaven, K Sapp, AJ Sodt - Biophysical Journal, 2024 - cell.com
Biological membranes are constituted of a multitude of different lipid types and membrane-
associated proteins, each of which affect the local mechanical properties of the membrane in …