Ambient PM2. 5 chronic exposure leads to cognitive decline in mice: From pulmonary to neuronal inflammation

Y Shou, X Zhu, D Zhu, H Yin, Y Shi, M Chen, L Lu… - Toxicology letters, 2020 - Elsevier
Abstract Fine particulate matter 2.5 (PM 2.5), one of the main components of air pollutants,
seriously threatens human health. Possible neuronal dysfunction induced by PM 2.5 has …

Atmospheric particulate matter impairs cognition by modulating synaptic function via the nose-to-brain route

C Liang, Y Jiang, T Zhang, Y Ji, Y Zhang, Y Sun… - Science of The Total …, 2023 - Elsevier
Atmospheric particulate matter (PM), a ubiquitous air pollutant, is the leading environmental
risk factor for mortality worldwide. Experimental and epidemiological studies consistently …

PM2. 5 impairs neurobehavior by oxidative stress and myelin sheaths injury of brain in the rat

Q Zhang, Q Li, J Ma, Y Zhao - Environmental pollution, 2018 - Elsevier
Air particulate matter (PM) is a serious environmental problem that has been found to cause
neuropathological disorders. Although the general toxicity of PM2. 5 has been intensively …

Neurodevelopmental toxicity induced by PM2. 5 Exposure and its possible role in Neurodegenerative and mental disorders

X Liu, J Huang, C Song, T Zhang… - Human & …, 2023 - journals.sagepub.com
Recent extensive evidence suggests that ambient fine particulate matter (PM2. 5, with an
aerodynamic diameter≤ 2.5 μm) may be neurotoxic to the brain and cause central nervous …

[HTML][HTML] A review of respirable fine particulate matter (PM2. 5)-induced brain damage

W Li, G Lin, Z Xiao, Y Zhang, B Li, Y Zhou… - Frontiers in Molecular …, 2022 - frontiersin.org
Respirable fine particulate matter (PM2. 5) has been one of the most widely publicied
indicators of pollution in recent years. Epidemiological studies have established a strong …

Comprehensive hippocampal metabolite responses to PM2. 5 in young mice

X Ning, B Li, T Ku, L Guo, G Li, N Sang - Ecotoxicology and Environmental …, 2018 - Elsevier
Abstract Fine particulate matter (PM 2.5) exposure alters brain development, clinical
cognition and behavior in childhood. Previous studies of this subject have mainly been …

Exposure to PM2. 5 induces neurotoxicity, mitochondrial dysfunction, oxidative stress and inflammation in human SH-SY5Y neuronal cells

CH Lin, CJB Nicol, C Wan, SJ Chen, RN Huang… - Neurotoxicology, 2022 - Elsevier
Ambient air pollution is a global public health issue. Recent evidence suggests that
exposure to fine aerosolized particulate matter (PM) as small as≤ 2.5 microns (PM 2.5) is …

Ambient PM2.5-induced brain injury is associated with the activation of PI3K/AKT/FoxO1 pathway

L Song, K Pan, X Du, S Jiang, X Zeng, J Zhang… - … Science and Pollution …, 2021 - Springer
Abstract PM 2.5-related neurological and mental diseases, such as cognitive impairment
and stroke, tend to cause disability. Six-week-old male C57BL/6 mice were divided into 6 …

[HTML][HTML] The air we breathe: air pollution as a prevalent proinflammatory stimulus contributing to neurodegeneration

M Jankowska-Kieltyka, A Roman… - Frontiers in Cellular …, 2021 - frontiersin.org
Air pollution is regarded as an important risk factor for many diseases that affect a large
proportion of the human population. To date, accumulating reports have noted that …

PM2. 5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain

T Ku, X Ji, Y Zhang, G Li, N Sang - Chemosphere, 2016 - Elsevier
Air pollution is a serious environmental health problem that has been previously associated
with neuropathological disorders. However, current experimental evidence mainly focuses …