Tuft cells are more than guardian chemosensory elements of the digestive tract. They
produce a variety of immunological effector molecules in response to stimulation; moreover …

A recent surge of interest in tuft cells, which are chemosensory intestinal epithelial cells, has
uncovered new functional roles for these cells in colorectal cancer, metabolic signaling, and …

The intestine is a powerful digestive system and one of the most sophisticated
immunological organs. Evidence shows that tuft cells (TCs), a kind of epithelial cell with …

The interests in intestinal epithelial tuft cells, their basic physiology, involvement in immune
responses and relevance for gut diseases, have increased dramatically over the last fifteen …

The intestinal epithelium plays crucial roles in maintaining gut homeostasis. A key function
consists in constituting a physical and chemical barrier between self and non-self …

Since their discovery> 60 years ago, tuft cells have intrigued and mystified researchers.
Early studies focused on the unique morphology of tuft cells and their distribution pattern …

Background Colonic tuft cells are epithelial chemosensory cells involved in barrier integrity,
modulation of inflammatory responses and gut homeostasis. Recent evidence indicates an …

Tuft cells are a rare and morphologically distinct chemosensory cell type found throughout
many organs, including the gastrointestinal tract. These cells were identified by their unique …

Intestinal tuft cells are a morphologically unique cell type, best characterized by striking
microvilli that form an apical tuft. These cells represent approximately 0.5% of gut epithelial …

Dclk1-expressing tuft cells constitute a unique intestinal epithelial lineage that is distinct from
enterocytes, Paneth cells, goblet cells, and enteroendocrine cells. Tuft cells express taste …