Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in humans and
is a significant source of morbidity and mortality. Despite its prevalence, our mechanistic …

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. A variety of animal
models have been used to study the pathophysiology of AF, including molecular basis, ion …

Understanding the mechanism of re-entrant arrhythmias in the past 30 years has allowed
the development of almost curative therapies for many rhythm disturbances. The complex …

Studies in animal models have provided extremely important insights about atrial fibrillation
(AF). The classic mechanisms that still form the framework for our understanding of AF (focal …

Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is associated
with substantial morbidity and mortality. Current treatment options for AF have significant …

Arrhythmias are common and contribute substantially to cardiovascular morbidity and
mortality. The underlying pathophysiology of arrhythmias is complex and remains …

This brief review looks back to the major theoretical, experimental, and clinical work on the
dynamics and mechanisms of atrial fibrillation (AF). Its goal is to highlight the most important …

Cardiac arrhythmias are a significant cause of morbidity and mortality worldwide, accounting
for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …

The normal mechanical functioning of the heart depends on proper electrical functioning,
reflected in the sequential activation of pacemaker cells, and the normal propagation of …

Background Although∼ 20% of the elderly population develops atrial fibrillation (AF), little is
known about the mechanisms. Heart failure with preserved ejection fraction (HFpEF), which …