Organophosphates, useful agents as pesticides, also represent a serious danger due to
their high acute toxicity. There is indication that oximes, when administered before …

Aims: Organophosphates (OPCs), useful agents as pesticides, also represent a serious
health hazard. Standard therapy with atropine and established oxime-type enzyme …

Oximes are cholinesterase reactivators used in organophosphorus poisoning. Clinical
experience with pralidoxime (PRX) and other oximes is disappointing and their routine use …

Oximes are cholinesterase reactivators used in organophosphorus compound poisoning.
The purpose of the study was to compare the protective effect of the K-oximes (K-27 and K …

K‐oximes have recently been developed in the search for efficacious broad‐band
reactivators of acetylcholinesterase (AChE) inhibited by organophosphorus compounds …

Standard therapy of Organophosphorus Compound (OPC) poisoning with oxime-type
acetylcholinesterase (AChE) reactivators is unsatisfactory. New bispyridinium oximes have …

There is a clear need for broad‐spectrum cholinesterase reactivators (active against a
multitude of organophosphorus ester enzyme inhibitors) with a higher efficacy than …

Oximes are cholinesterase reactivators of use in poisoning with organophosphorus
compounds. Pralidoxime (PRX) is used clinically as an adjunct to atropine in such exposure …

Pyridostigmine (PSTG) is a carbamate inhibitor of cholinesterases. Carbamates are known
to confer some protection from the lethal effects of (some) organophosphorus compounds …

Background: Reversible cholinesterase inhibitors, when given prophylactically before
exposure to organophosphates, are able to decrease organophosphate-induced mortality …