RNA G-quadruplexes (rG4s): genomics and biological functions
Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …
have been first observed decades ago. Over the years, these four-stranded structural motifs …
Properties and biological impact of RNA G-quadruplexes: from order to turmoil and back
P Kharel, G Becker, V Tsvetkov… - Nucleic acids research, 2020 - academic.oup.com
Abstract Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …
Detecting RNA G-quadruplexes (rG4s) in the transcriptome
CK Kwok, G Marsico… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
SUMMARY RNA G-quadruplex (rG4) secondary structures are proposed to play key roles in
fundamental biological processes that include the modulation of transcriptional, co …
fundamental biological processes that include the modulation of transcriptional, co …
RNA G-quadruplexes in biology: principles and molecular mechanisms
Abstract G-quadruplexes (G4s) are extremely stable DNA or RNA secondary structures
formed by sequences rich in guanine. These structures are implicated in many essential …
formed by sequences rich in guanine. These structures are implicated in many essential …
G-Quadruplexes in RNA biology: recent advances and future directions
RNA G-quadruplexes (RG4s) are four-stranded structures known to control gene expression
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells
Guanine-rich RNA sequences can fold into four-stranded structures, termed G-quadruplexes
(G4-RNAs), whose biological roles are poorly understood, and in vivo existence is debated …
(G4-RNAs), whose biological roles are poorly understood, and in vivo existence is debated …
RNA G-quadruplex structures control ribosomal protein production
Four-stranded G-quadruplex (G4) structures form from guanine-rich tracts, but the extent of
their formation in cellular RNA and details of their role in RNA biology remain poorly defined …
their formation in cellular RNA and details of their role in RNA biology remain poorly defined …
QUADRatlas: the RNA G-quadruplex and RG4-binding proteins database
S Bourdon, P Herviou, L Dumas… - Nucleic Acids …, 2023 - academic.oup.com
Abstract RNA G-quadruplexes (RG4s) are non-canonical, disease-associated post-
transcriptional regulators of gene expression whose functions are driven by RNA-binding …
transcriptional regulators of gene expression whose functions are driven by RNA-binding …
Directly lighting up RNA G-quadruplexes from test tubes to living human cells
Abstract RNA G-quadruplexes (G4s) are one of the key components of the transcriptome that
act as efficient post-transcriptional regulatory elements in living cells. To conduct further …
act as efficient post-transcriptional regulatory elements in living cells. To conduct further …
Detection of genomic G-quadruplexes in living cells using a small artificial protein
K Zheng, J Zhang, Y He, J Gong, C Wen… - Nucleic acids …, 2020 - academic.oup.com
Abstract G-quadruplex (G4) structures formed by guanine-rich nucleic acids are implicated
in essential physiological and pathological processes and serve as important drug targets …
in essential physiological and pathological processes and serve as important drug targets …