Context As the number of transgender (trans) people (including those who are binary and/or
nonbinary identified) seeking gender-affirming hormone therapy rises, endocrinologists are …

Background Clinical guidelines recommend laboratory monitoring of transgender persons
on cross-sex hormone therapy, but gender-specific reference intervals leave clinicians with …

Background Many laboratory tests are reported and interpreted with sex-specific reference
intervals. However, transgender individuals receiving masculinizing or feminizing hormone …

BACKGROUND For transgender individuals taking hormone therapy (HT), data on
laboratory values are limited, and the effects on laboratory values cannot be easily …

Background Known physiological changes occur while transgender patients are taking
hormone therapy (HT). However, knowledge is limited about when laboratory values …

Background Gender-affirming hormone therapy with either estradiol or testosterone is
commonly prescribed for transgender individuals. Masculinizing or feminizing hormone …

BACKGROUND Transgender is an umbrella term used to describe individuals who identify
with a gender incongruent to or variant from their sex recorded at birth. Affirming gender …

Background Gender-affirming therapy with testosterone is commonly prescribed to aid in the
masculinization of transgender men. Sex-hormone concentrations are routinely measured …

Background Transgender women and nonbinary people seeking feminizing therapy are
often prescribed estrogen as a gender-affirming hormone, which will alter their reproductive …

Objective Transgender individuals sometimes report a lack of physical change during
hormone treatment, such as alterations in muscle tone or fat distribution. Identifying …