The assembly of the primordial follicles early in ovarian development and the subsequent
development and transition of the primordial follicle to the primary follicle are critical …

The assembly of the developmentally arrested primordial follicle and the subsequent
transition of the primordial follicle to the primary follicle are critical processes in normal …

Specific factors that mediate local cell—cell interactions in the ovary related to the initiation
and progression of follicle development will be discussed. Recently, several factors …

BACKGROUND The first small follicles to appear in the mammalian ovaries are primordial
follicles. The initial pool of primordial follicles serves as the source of developing follicles …

Mammalian ovaries consist of follicles as basic functional units. Each follicle comprised an
innermost oocyte and several surrounding flattened granulosa cells. Unlike males …

Primordial germ cell migration and homing within the gonadal ridge during early embryo
development requires oocyte-secreted polypeptide, growth factors, growth and …

The preantral-early antral follicle transition is the penultimate stage of follicular development
in terms of gonadotropin dependence and follicle destiny (growth versus atresia). Follicular …

[Frontiers in Bioscience 7, d1990-1996, September 1, 2002] 1990 CELL-CELL INTERACTIONS
IN PRIMORDIAL FOLLICLE ASSEMBLY AND DEVEL Page 1 [Frontiers in Bioscience 7 …

The differentiation of primordial germ cells (PGCs) into functional oocytes is important for the
continuation of species. In mammals, PGCs begin to differentiate into oocytes during …

The mammalian ovary has two main functions—producing mature oocytes for fertilization
and secreting hormones for maintaining the ovarian endocrine functions. Both functions are …