Hypoxic pulmonary vasoconstriction

JT Sylvester, LA Shimoda, PI Aaronson… - Physiological …, 2012 - journals.physiology.org
It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …

Hypoxic pulmonary vasoconstriction: mechanisms and controversies

PI Aaronson, TP Robertson, GA Knock… - The Journal of …, 2006 - Wiley Online Library
The pulmonary circulation differs from the systemic in several important aspects, the most
important being that pulmonary arteries constrict to moderate physiological (∼ 20–60 mmHg …

The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels

EK Weir, SL Archer - The FASEB journal, 1995 - Wiley Online Library
Hypoxia causes constriction in small pulmonary arteries and dilatation in systemic arteries.
Hypoxic pulmonary vasoconstriction (HPV) is an important mechanism by which pulmonary …

Basic features of hypoxic pulmonary vasoconstriction in mice

N Weissmann, E Akkayagil, K Quanz… - Respiratory physiology …, 2004 - Elsevier
Hypoxic pulmonary vasoconstriction (HPV) matches lung perfusion with ventilation which
tends to optimize pulmonary gas exchange. Investigations using genetically engineered …

Mechanisms of hypoxic pulmonary vasoconstriction: can anyone be right?

JPT Ward, PI Aaronson - Respiration physiology, 1999 - Elsevier
Despite extensive studies over many years, there is still no real consensus regarding the
mechanisms responsible for hypoxic pulmonary vasoconstriction (HPV). This is partially …

Hypoxic pulmonary vasoconstriction

ER Swenson - High altitude medicine & biology, 2013 - liebertpub.com
Abstract Swenson, Erik R. Hypoxic pulmonary vasoconstriction. High Alt Med Biol 14: 101–
110, 2013.—Hypoxic pulmonary vasoconstriction (HPV) continues to fascinate …

Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms

N Sommer, A Dietrich, RT Schermuly… - European …, 2008 - Eur Respiratory Soc
Hypoxic pulmonary vasoconstriction (HPV), also known as the von Euler–Liljestrand
mechanism, is a physiological response to alveolar hypoxia which distributes pulmonary …

The endothelium in hypoxic pulmonary vasoconstriction

B Grimmer, WM Kuebler - Journal of Applied Physiology, 2017 - journals.physiology.org
Hypoxic pulmonary vasoconstriction (HPV) in combination with hypercapnic pulmonary
vasoconstriction redistributes pulmonary blood flow from poorly aerated to better ventilated …

Oxygen sensing and signal transduction in hypoxic pulmonary vasoconstriction

N Sommer, I Strielkov, O Pak… - European Respiratory …, 2016 - Eur Respiratory Soc
Hypoxic pulmonary vasoconstriction (HPV), also known as the von Euler–Liljestrand
mechanism, is an essential response of the pulmonary vasculature to acute and sustained …

Hypoxic pulmonary vasoconstriction: mechanisms of oxygen-sensing

AM Evans, DG Hardie, C Peers… - Current Opinion in …, 2011 - journals.lww.com
HPV supports ventilation–perfusion matching in the lung by diverting blood flow away from
oxygen-deprived areas towards regions rich in O 2. However, in diseases such as …