Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

[图书][B] Hyperpolarization methods in NMR spectroscopy

LT Kuhn, Ü Akbey - 2013 - Springer
Nuclear magnetic resonance (NMR) spectroscopy is arguably one of the most potent
experimental techniques for probing molecular structure at ultra-high resolution both in …

Brute-force hyperpolarization for NMR and MRI

ML Hirsch, N Kalechofsky, A Belzer… - Journal of the …, 2015 - ACS Publications
Hyperpolarization (HP) of nuclear spins is critical for ultrasensitive nuclear magnetic
resonance (NMR) and magnetic resonance imaging (MRI). We demonstrate an approach …

A platform for designing hyperpolarized magnetic resonance chemical probes

H Nonaka, R Hata, T Doura, T Nishihara… - Nature …, 2013 - nature.com
Hyperpolarization is a highly promising technique for improving the sensitivity of magnetic
resonance chemical probes. Here we report [15N, D9] trimethylphenylammonium as a …

Over 50 % 1H and 13C Polarization for Generating Hyperpolarized Metabolites—A para‐Hydrogen Approach

S Korchak, S Mamone, S Glöggler - ChemistryOpen, 2018 - Wiley Online Library
Abstract para‐Hydrogen‐induced polarization (PHIP) is a method to rapidly generate
hyperpolarized compounds, enhancing the signal of nuclear magnetic resonance (NMR) …

Application of Parahydrogen Induced Polarization Techniques in NMR Spectroscopy and Imaging

SB Duckett, RE Mewis - Accounts of chemical research, 2012 - ACS Publications
Magnetic resonance provides a versatile platform that allows scientists to examine many
different types of phenomena. However, the sensitivity of both NMR spectroscopy and MRI is …

SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization

DA Barskiy, S Knecht, AV Yurkovskaya… - Progress in Nuclear …, 2019 - Elsevier
In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

LIGHT-SABRE enables efficient in-magnet catalytic hyperpolarization

T Theis, M Truong, AM Coffey, EY Chekmenev… - Journal of Magnetic …, 2014 - Elsevier
Nuclear spin hyperpolarization overcomes the sensitivity limitations of traditional NMR and
MRI, but the most general method demonstrated to date (dynamic nuclear polarization) has …

Transfer of SABRE-derived hyperpolarization to spin-1/2 heteronuclei

AN Pravdivtsev, AV Yurkovskaya, H Zimmermann… - Rsc Advances, 2015 - pubs.rsc.org
In this paper, we describe a method of hyper-polarizing “insensitive” Nuclear Magnetic
Resonance (NMR) nuclei by exploiting the SABRE (Signal Amplification By Reversible …

Synergies between hyperpolarized NMR and microfluidics: A review

J Eills, W Hale, M Utz - Progress in Nuclear Magnetic Resonance …, 2022 - Elsevier
Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two
dynamic, but until recently quite distinct, fields of research. Recent developments in both …