Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8α+ dendritic cells

LF Poulin, M Salio, E Griessinger… - Journal of Experimental …, 2010 - rupress.org
In mouse, a subset of dendritic cells (DCs) known as CD8α+ DCs has emerged as an
important player in the regulation of T cell responses and a promising target in vaccination …

CX3CR1+ CD8α+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells

L Bar-On, T Birnberg, KL Lewis… - Proceedings of the …, 2010 - National Acad Sciences
Lymphoid organs are characterized by a complex network of phenotypically distinct dendritic
cells (DC) with potentially unique roles in pathogen recognition and immunostimulation …

[HTML][HTML] Subsets of CD1c+ DCs: Dendritic Cell Versus Monocyte Lineage

L Heger, TP Hofer, V Bigley, IJM de Vries… - Frontiers in …, 2020 - frontiersin.org
Currently three bona fide dendritic cell (DC) types are distinguished in human blood. Herein
we focus on type 2 DCs (DC2s) and compare the three defining markers CD1c, CD172, and …

[HTML][HTML] Transcriptional and functional analysis of CD1c+ human dendritic cells identifies a CD163+ subset priming CD8+ CD103+ T cells

P Bourdely, G Anselmi, K Vaivode, RN Ramos… - Immunity, 2020 - cell.com
Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the
diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here …

CD8α+ dendritic cells originate from the CD8α dendritic cell subset by a maturation process involving CD8α, DEC-205, and CD24 up-regulation

GM del Hoyo, P Martı́n, CF Arias… - Blood, The Journal …, 2002 - ashpublications.org
CD8α+ and CD8α− dendritic cells (DCs) have been considered as independent DC
subpopulations both ontogenetically and functionally during recent years. However, it has …

Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors

Z Liu, H Wang, Z Li, RJ Dress, Y Zhu, S Zhang… - Immunity, 2023 - cell.com
Conventional dendritic cells (cDCs) are professional antigen-presenting cells that control the
adaptive immune response. Their subsets and developmental origins have been intensively …

CD8α+ and CD8α Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo

R Maldonado-López, T De Smedt, P Michel… - The Journal of …, 1999 - rupress.org
Cells of the dendritic family display some unique properties that confer to them the capacity
to sensitize naive T cells in vitro and in vivo. In the mouse, two subclasses of dendritic cells …

Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species

V Contreras, C Urien, R Guiton… - The Journal of …, 2010 - journals.aai.org
The mouse lymphoid organ-resident CD8α+ dendritic cell (DC) subset is specialized in Ag
presentation to CD8+ T cells. Recent evidence shows that mouse nonlymphoid tissue …

Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

SL Jongbloed, AJ Kassianos, KJ McDonald… - Journal of Experimental …, 2010 - rupress.org
The characterization of human dendritic cell (DC) subsets is essential for the design of new
vaccines. We report the first detailed functional analysis of the human CD141+ DC subset …

Relationships among murine CD11chigh dendritic cell subsets as revealed by baseline gene expression patterns

AD Edwards, D Chaussabel, S Tomlinson… - The Journal of …, 2003 - journals.aai.org
The functional relationships and properties of different subtypes of dendritic cells (DC)
remain largely undefined. To better characterize these cells, we used global gene analysis …