Several recent breakthroughs have provided notable insights into the pathogenesis of
amyotrophic lateral sclerosis (ALS), with some even shifting our thinking about this …

Amyotrophic lateral sclerosis (ALS) is characterized phenotypically by progressive
weakness and neuropathologically by loss of motor neurons. Phenotypically, there is …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of the motor
neurons, which results in weakness and atrophy of voluntary skeletal muscles. Treatments …

Amyotrophic lateral sclerosis (ALS) is increasingly considered to be a disorder of multiple
etiologies that have in common progressive degeneration of both upper and lower motor …

Amyotrophic lateral sclerosis is a degenerative disease affecting the motor neurons. In spite
of our growing insights into its biology, it remains a lethal condition. The identification of the …

Amyotrophic lateral sclerosis (ALS) is characterized by the selective degeneration of motor
neurons. Two independent studies in this issue show that astrocytes expressing a mutation …

Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Amyotrophic lateral sclerosis (ALS) is a devastating degenerative disease characterized by
progressive loss of motor neurons in the motor cortex, brainstem, and spinal cord. Although …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are age-related
neurodegenerative diseases in which predominantly motor neurons and cerebral cortex …

Amyotrophic lateral sclerosis (ALS) is the most common adult-onset paralytic disorder,
characterized mainly by a loss of motor neurons (MNs) in the CNS. Over the past decades …