The use of food-grade organisms as recombinant vaccine expression hosts and delivery
vehicles has been explored during the past 25 years, opening new avenues for vaccinology …

Abstract Food-grade Lactic Acid Bacteria (LAB) have been safely consumed for centuries by
humans in fermented foods. Thus, they are good candidates to develop novel oral vectors …

Gram‐positive, nonpathogenic lactic acid bacteria (LAB) are considered to be promising
candidates for the development of novel, safe production and delivery systems of …

The development of new strategies for the delivery of vaccine antigens or immune
modulators to the mucosal tissue includes innovative approaches such as the use of …

Probiotics have great potential to be engineered into oral vaccine delivery systems, which
can facilitate elicitation of mucosal immunity without latent risks of pathogenicity. Combined …

Needle free vaccines have a several advantages and very attractive way for vaccination. In a
body, mucosal surfaces provide a universal entry portal for all the known and emerging …

Mucosal routes for vaccine delivery offer several advantages over systemic inoculation from
both immunological and practical points of view. The development of efficient mucosal …

Highlights•Recombinant lactococci and lactobacilli have been successfully used in the last
years as safe mucosal delivery vectors for molecules of health interest.•The delivery of …

The mucosal surface is the largest route through which pathogens enter the human body. To
control the outbreak of mucosal infectious diseases, we must use our knowledge of the …

Lactic acid bacteria (LAB) have a long history of safe exploitation by humans, being used for
centuries in food production and preservation and as probiotic agents to promote human …