The known genetic architecture of blood pressure now comprises> 30 genes, with rare
variants resulting in monogenic forms of hypertension or hypotension and> 1,477 common …

Contemporary genomic tools now allow the fast and reliable genotyping of hundreds of
thousands of variants and permit an unbiased interrogation of the common variability across …

Hypertension (HTN) is quantitatively the major cardiovascular risk factor and responsible
for∼ 50% of cardiovascular morbidity and mortality. Blood pressure (BP) is also a classical …

The elucidation of genes implicated in Mendelian forms of hypertension demonstrates rare
variants with substantial effects are responsible, and often these genes lie within pathways …

The genetic architecture of blood pressure (BP) now includes more than 30 genes, with rare
mutations resulting in inherited forms of hypertension or hypotension, and 1477 common …

Elevated blood pressure is a common, heritable cause of cardiovascular disease worldwide.
To date, identification of common genetic variants influencing blood pressure has proven …

Hypertension is a major modifiable risk factor for renal, cardiovascular, and cerebrovascular
disease, and a leading underlying cause of global mortality and morbidity. 1 Incremental …

Hypertension is a multifactorial disorder that probably results from the inheritance of a
number of susceptibility genes and involves multiple environmental determinants. Existing …

We are at the beginning of a biological revolution, spurred on by the Human Genome
Project and associated studies. Within the next few years, expressed sequence tags (ESTs) …

Longitudinal electronic health records on 99,785 Genetic Epidemiology Research on Adult
Health and Aging (GERA) cohort individuals provided 1,342,814 systolic and diastolic blood …