This review is focused on the structural and physicochemical aspects of metal cation
coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G …

G-quadruplexes are guanine-rich nucleic acids that fold by forming successive quartets of
guanines (the G-tetrads), stabilized by intra-quartet hydrogen bonds, inter-quartet stacking …

Topologies of G-quadruplexes depend on oligonucleotide sequences and on environmental
factors, and the diversity of G-quadruplex topologies complicates investigation of functions of …

G-quadruplexes adopt various folding topologies, but information on their folding pathways
remains scarce. Here, we used electrospray mass spectrometry to detect and quantify the …

The quadruplex forming G-rich sequences are unevenly distributed throughout the human
genome. Their enrichment in oncogenic promoters and telomeres has generated interest in …

Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that
involve G-quartets linked by loop nucleotides. The structural and topological diversity of G …

There are many structures that can be adopted by nucleic acids other than the famous
Watson–Crick duplex form. This tutorial review describes the guanine rich G-quadruplex …

Guanine quadruplex (G‐quadruplex) structures are formed by guanine‐rich
oligonucleotides. Because of their in vivo and in vitro importance, numerous studies have …

G‐quadruplexes have attracted growing interest in recent years due to their occurrence in
vivo and their possible biological functions. In addition to being promising targets for drug …

G-quadruplexes are non-canonical secondary structures found in guanine rich regions of
DNA and RNA. Reports have indicated the wide occurrence of RNA G-quadruplexes across …