Hox proteins are a deeply conserved group of transcription factors originally defined for their
critical roles in governing segmental identity along the antero-posterior (AP) axis in …

Despite decades of research, morphogenesis along the various body axes remains one of
the major mysteries in developmental biology. A milestone in the field was the realisation …

Since their discovery Hox genes have been at the core of the established models explaining
the development and evolution of the vertebrate body plan as well as its paired …

Hox genes are a group of genes that specify structures along the anteroposterior axis in
bilaterians. Although in many cases they do so by modifying a homologous structure with a …

Functional diversification of body parts is dependent on the formation of specialized
structures along the various body axes. In animals, region-specific morphogenesis along the …

Background Hox genes are master regulatory genes that specify positional identities during
axial development in animals. Discoveries regarding their concerted expression patterns …

Hox genes pattern the anterior-posterior axis of animals and are posited to drive animal
body plan evolution, yet their precise role in evolution has been difficult to determine. Here …

Hox genes encode evolutionarily conserved transcription factors that control the
morphological diversification along the anteroposterior (A/P) body axis. Expressed in …

Most animals exhibit distinctive and diverse morphological features on their anterior‐
posterior body axis. However, underneath the variation in design and developmental …

Hox genes, which are important for determining regional identity in organisms as diverse as
flies and humans, are typically considered to be under strong evolutionary constraints …