It is generally accepted that many genes present in vertebrate genomes owe their origin to
two whole-genome duplications that occurred deep in the ancestry of the vertebrate lineage …

Background It has been proposed that more than 450 million years ago, two successive
whole genome duplications took place in a marine chordate lineage before leading to the …

Researchers, supported by data from polyploid plants, have suggested that whole genome
duplication (WGD) may induce genomic instability and rearrangement, an idea which could …

The sea lamprey (Petromyzon marinus) serves as a comparative model for reconstructing
vertebrate evolution. To enable more informed analyses, we developed a new assembly of …

Vertebrates originated in the lower Cambrian. Their diversification and morphological
innovations have been attributed to large-scale gene or genome duplications at the origin of …

Two rounds of whole-genome duplications are thought to have played an important role in
the establishment of gene repertoires in vertebrates. These events occurred during chordate …

The hypothesis that the relatively large and complex vertebrate genome was created by two
ancient, whole genome duplications has been hotly debated, but remains unresolved. We …

It has been proposed that two events of duplication of the entire genome occurred early in
vertebrate history (2R hypothesis). Several phylogenetic studies with a few gene families …

Polyploidy or whole-genome duplication (WGD) is a major event that drastically reshapes
genome architecture and is often assumed to be causally associated with organismal …

Lampreys are representatives of an ancient vertebrate lineage that diverged from our own∼
500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) …