Cardiovascular risk factors and future risk of Alzheimer's disease

RFAG de Bruijn, MA Ikram - BMC medicine, 2014 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disorder in elderly people,
but there are still no curative options. Senile plaques and neurofibrillary tangles are …

Vascular abnormalities: The insidious pathogenesis of Alzheimer's disease☆

J Shi, G Perry, MA Smith, RP Friedland - Neurobiology of Aging, 2000 - Elsevier
Alzheimer's disease (AD) and cerebrovascular dementia (CVD) are two major causes of
senile dementia in elderly individuals. Mounting evidence from epidemiological, clinical, and …

Vascular risk factors and Alzheimer's disease

JT O'Brien, HS Markus - BMC medicine, 2014 - Springer
Vascular factors are now established risk factors for cognitive decline, both for dementia and
its two main subtypes: Alzheimer's disease (AD) and vascular dementia. Their impact likely …

Preventing Alzheimer's disease by targeting vascular risk factors: hope and gap

C Qiu - Journal of Alzheimer's Disease, 2012 - content.iospress.com
Alzheimer's disease (AD) is a major cause of functional dependence, poor quality of life,
institutionalization, and mortality among elderly people. As a multifactorial disorder, AD has …

Alzheimer's dementia: pathogenesis and impact of cardiovascular risk factors on cognitive decline

P Wanleenuwat, P Iwanowski… - Postgraduate …, 2019 - Taylor & Francis
Alzheimer's disease (AD) is the most common form of dementia manifesting as alterations in
cognitive abilities, behavior, and deterioration in memory which is progressive, leading to …

Dementia, stroke, and vascular risk factors; a review

R Sahathevan, A Brodtmann… - International Journal of …, 2012 - journals.sagepub.com
Interest in dementia has increased over the past few decades. Stroke is an important cause
of cognitive problems. The term vascular cognitive impairment is now used to describe …

Cardiovascular Disease and Alzheimer's Disease: The Heart–Brain Axis

A Saeed, O Lopez, A Cohen… - Journal of the American …, 2023 - Am Heart Assoc
Cardiovascular disease (CVD) remains one of the leading causes of morbidity and mortality
in aging adults across the United States. Prior studies indicate that the presence of …

Alzheimer's disease, cerebrovascular disease, and the β-amyloid cascade

K Honjo, SE Black, NPLG Verhoeff - Canadian Journal of …, 2012 - cambridge.org
Alzheimer's disease (AD), considered the commonest neurodegenerative cause of
dementia, is associated with hallmark pathologies including extracellular amyloid-β protein …

[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis

CY Santos, PJ Snyder, WC Wu, M Zhang… - Alzheimer's & Dementia …, 2017 - Elsevier
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

Alzheimer's Disease and Vascular Aging: JACC Focus Seminar

M Cortes-Canteli, C Iadecola - Journal of the American College of …, 2020 - jacc.org
Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative
condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in …