In PubMed, it is possible to find more than 40,000 papers on embryo evaluation in various
species. However, there is no consensus or gold standard method on how to assess their …

Embryo imaging has long been a critical tool for in vitro fertilization laboratories, aiding in
morphological assessment of embryos, which remains the primary tool for embryo selection …

Assisted reproduction is one of the significant tools to treat human infertility. Morphological
assessment is the primary method to determine sperm and embryo viability during in vitro …

In recent years, we have witnessed an unprecedented advancement of light microscopy
techniques which has allowed us to better understand biological processes occurring during …

Background Super-resolution fluorescence microscopy performed via 3D structured
illumination microscopy (3D-SIM) is well established on flat, adherent cells. However …

Elective single-embryo transfer has emerged as the most effective method for reducing the
incidence of multiple births associated with assisted-reproductive technology (ART). Over …

Gamete and embryo visualization using brightfield or differential interference contrast is the
primary means of cell assessment used to gauge developmental progress and quality. With …

Embryo quality is an important determinant of successful implantation and a resultant live
birth. Current clinical approaches for evaluating embryo quality rely on subjective …

Over the last two decades, methodologies for assessing embryo implantation potential have
emerged, including time-lapse imaging systems, various “-omics” techniques (genomics …

Making accurate microscopic images today is not easy. We are on the cusp of reliable 4-
dimensional (4D) imaging, which is capable of revealing the dynamic nature of cells and …