Epi-illumination gradient light interference microscopy for imaging opaque structures

ME Kandel, C Hu, G Naseri Kouzehgarani… - Nature …, 2019 - nature.com
Multiple scattering and absorption limit the depth at which biological tissues can be imaged
with light. In thick unlabeled specimens, multiple scattering randomizes the phase of the field …

Phase-gradient microscopy in thick tissue with oblique back-illumination

TN Ford, KK Chu, J Mertz - Nature Methods, 2012 - nature.com
Phase-contrast techniques, such as differential interference contrast microscopy, are widely
used to obtain morphological images of unstained biological samples. The transillumination …

Structured illumination quantitative phase microscopy for enhanced resolution amplitude and phase imaging

S Chowdhury, J Izatt - Biomedical optics express, 2013 - opg.optica.org
Structured illumination microscopy (SIM) is an established microscopy technique typically
used to image samples at resolutions beyond the diffraction limit. Until now, however …

Gradient light interference microscopy for 3D imaging of unlabeled specimens

TH Nguyen, ME Kandel, M Rubessa… - Nature …, 2017 - nature.com
Multiple scattering limits the contrast in optical imaging of thick specimens. Here, we present
gradient light interference microscopy (GLIM) to extract three-dimensional information from …

Spatial light interference microscopy: principle and applications to biomedicine

X Chen, ME Kandel, G Popescu - Advances in optics and photonics, 2021 - opg.optica.org
In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …

High-resolution transport-of-intensity quantitative phase microscopy with annular illumination

C Zuo, J Sun, J Li, J Zhang, A Asundi, Q Chen - Scientific reports, 2017 - nature.com
For quantitative phase imaging (QPI) based on transport-of-intensity equation (TIE), partially
coherent illumination provides speckle-free imaging, compatibility with brightfield …

Epi-mode tomographic quantitative phase imaging in thick scattering samples

P Ledwig, FE Robles - Biomedical optics express, 2019 - opg.optica.org
Quantitative phase imaging (QPI) is an important tool in biomedicine that allows for the
microscopic investigation of live cells and other thin, transparent samples. Importantly, this …

Instantaneous spatial light interference microscopy

H Ding, G Popescu - Optics express, 2010 - opg.optica.org
We present Instantaneous Spatial Light Interference Microscopy (iSLIM) as a new
quantitative phase method that combines the benefits of white light illumination in Zernike's …

Tomographic phase microscopy

W Choi, C Fang-Yen, K Badizadegan, S Oh, N Lue… - Nature …, 2007 - nature.com
We report a technique for quantitative three-dimensional (3D) mapping of refractive index in
live cells and tissues using a phase-shifting laser interferometric microscope with variable …

Quantitative phase imaging using a partitioned detection aperture

AB Parthasarathy, KK Chu, TN Ford, J Mertz - Optics letters, 2012 - opg.optica.org
We present a technique to quantitatively image the phase of thin quasi-transparent samples
using extended source incoherent illumination and off-axis detection apertures. Our …