Extracellular matrix hydrogel therapies: In vivo applications and development

MT Spang, KL Christman - Acta biomaterialia, 2018 - Elsevier
Decellularized extracellular matrix (ECM) has been widely used for tissue engineering
applications and is becoming increasingly versatile as it can take many forms, including …

Extracellular matrix hydrogels from decellularized tissues: Structure and function

LT Saldin, MC Cramer, SS Velankar, LJ White… - Acta biomaterialia, 2017 - Elsevier
Extracellular matrix (ECM) bioscaffolds prepared from decellularized tissues have been
used to facilitate constructive and functional tissue remodeling in a variety of clinical …

The engineering and application of extracellular matrix hydrogels: a review

Y Zhang, Y Xu, J Gao - Biomaterials science, 2023 - pubs.rsc.org
This review provides an overview of the engineering and application of extracellular matrix
(ECM) hydrogels. ECM hydrogels are attractive materials for tissue engineering and …

Decellularized ECM hydrogels: prior use considerations, applications, and opportunities in tissue engineering and biofabrication

J Kort-Mascort, S Flores-Torres, O Peza-Chavez… - Biomaterials …, 2023 - pubs.rsc.org
Tissue development, wound healing, pathogenesis, regeneration, and homeostasis rely
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …

A hydrogel derived from decellularized dermal extracellular matrix

MT Wolf, KA Daly, EP Brennan-Pierce, SA Johnson… - Biomaterials, 2012 - Elsevier
The ECM of mammalian tissues has been used as a scaffold to facilitate the repair and
reconstruction of numerous tissues. Such scaffolds are prepared in many forms including …

Extracellular matrix particle–glycosaminoglycan composite hydrogels for regenerative medicine applications

V Beachley, G Ma, C Papadimitriou… - … Research Part A, 2018 - Wiley Online Library
Tissue extracellular matrix (ECM) is a complex material made up of fibrous proteins and
ground substance (glycosaminoglycans, GAGs) that are secreted by cells. ECM contains …

Engineering hydrogels as extracellular matrix mimics

H Geckil, F Xu, X Zhang, SJ Moon, U Demirci - Nanomedicine, 2010 - Taylor & Francis
Extracellular matrix (ECM) is a complex cellular environment consisting of proteins,
proteoglycans, and other soluble molecules. ECM provides structural support to mammalian …

Biocompatibility of hydrogel-based scaffolds for tissue engineering applications

S Naahidi, M Jafari, M Logan, Y Wang, Y Yuan… - Biotechnology …, 2017 - Elsevier
Recently, understanding of the extracellular matrix (ECM) has expanded rapidly due to the
accessibility of cellular and molecular techniques and the growing potential and value for …

Fractionation of an ECM hydrogel into structural and soluble components reveals distinctive roles in regulating macrophage behavior

PF Slivka, CL Dearth, TJ Keane, FW Meng… - Biomaterials …, 2014 - pubs.rsc.org
Extracellular matrix (ECM) derived from mammalian tissues has been utilized to repair
damaged or missing tissue and improve healing outcomes. More recently, processing of …

Synthetic mimics of the extracellular matrix: how simple is complex enough?

KA Kyburz, KS Anseth - Annals of biomedical engineering, 2015 - Springer
Cells reside in a complex and dynamic extracellular matrix where they interact with a myriad
of biophysical and biochemical cues that direct their function and regulate tissue …