The cancer preventive peptide lunasin from wheat inhibits core histone acetylation

HJ Jeong, JB Jeong, DS Kim, JH Park, JB Lee… - Cancer letters, 2007 - Elsevier
Lunasin is a unique 43-amino acid cancer preventive peptide initially reported in soybean
and barley and has been shown to be chemopreventive in mammalian cells and in a skin …

Inhibition of core histone acetylation by the cancer preventive peptide lunasin

HJ Jeong, JB Jeong, DS Kim… - Journal of agricultural …, 2007 - ACS Publications
Lunasin is a unique 43 amino acid soy peptide that has been shown to be chemopreventive
in mammalian cells and in a skin cancer mouse model in this work against oncogenes and …

Lunasin: a cancer-preventive soy peptide

BO de Lumen - Nutrition reviews, 2005 - academic.oup.com
Lunasin is a novel, cancer-preventive peptide whose efficacy against chemical carcinogens
and oncogenes has been demonstrated in mammalian cells and in a skin cancer mouse …

Lunasin is prevalent in barley and is bioavailable and bioactive in in vivo and in vitro studies

HJ Jeong, JB Jeong, CC Hsieh… - Nutrition and …, 2010 - Taylor & Francis
Lunasin, a unique 43-amino acid peptide found in a number of seeds, has been shown to be
chemopreventive in mammalian cells and in a skin cancer mouse model. To elucidate the …

The cancer preventive seed peptide lunasin from rye is bioavailable and bioactive

HJ Jeong, JR Lee, JB Jeong, JH Park… - Nutrition and …, 2009 - Taylor & Francis
Lunasin is a unique 43-amino acid peptide that has been shown to be chemopreventive in
mammalian cells and in a skin cancer mouse model against oncogenes and chemical …

Cancer-preventive peptide lunasin from Solanum nigrum L. inhibits acetylation of core histones H3 and H4 and phosphorylation of retinoblastoma protein (Rb)

JB Jeong, HJ Jeong, JH Park, SH Lee… - Journal of agricultural …, 2007 - ACS Publications
Lunasin, a unique 43 amino acid, 4.8 kDa cancer-chemopreventive peptide initially reported
in soybean and now found in barley and wheat, has been shown to be cancer …

Chemopreventive property of a soybean peptide (lunasin) that binds to deacetylated histones and inhibits acetylation

AF Galvez, N Chen, J Macasieb, BO de Lumen - Cancer research, 2001 - AACR
Lunasin is a unique 43-amino acid soybean peptide that contains at its carboxyl end:(a) nine
Asp (D) residues;(b) an Arg-Gly-Asp (RGD) cell adhesion motif; and (c) a predicted helix with …

Barley Lunasin Suppresses ras-Induced Colony Formation and Inhibits Core Histone Acetylation in Mammalian Cells

HJ Jeong, Y Lam, BO de Lumen - Journal of agricultural and food …, 2002 - ACS Publications
Lunasin is a novel peptide originally identified in soybean that suppresses chemical
carcinogen-induced transformation in mammalian cells and skin carcinogenesis in mice …

Lunasin, a novel seed peptide for cancer prevention

B Hernández-Ledesma, CC Hsieh, BO de Lumen - Peptides, 2009 - Elsevier
Carcinogenesis is a multistage process derived from a combination of multiple heritable and
environmental factors. It has been reported that populations consuming high levels of …

Relationship between lunasin's sequence and its inhibitory activity of histones H3 and H4 acetylation

B Hernández‐Ledesma, CC Hsieh… - Molecular nutrition & …, 2011 - Wiley Online Library
Scope: Dysfunction of histone acetyltransferases (HATs) or histone deacetylases (HDACs)
involved in histones acetylation has been associated with cancer. Inhibitors of these …