An air particulate pollutant induces neuroinflammation and neurodegeneration in human brain models

YJ Kang, HY Tan, CY Lee, H Cho - Advanced Science, 2021 - Wiley Online Library
Abstract Fine particulate matter (PM2. 5), a major component among air pollutants,
highlights as a global health concern. Several epidemiological studies show the correlation …

PM2. 5 impairs neurobehavior by oxidative stress and myelin sheaths injury of brain in the rat

Q Zhang, Q Li, J Ma, Y Zhao - Environmental pollution, 2018 - Elsevier
Air particulate matter (PM) is a serious environmental problem that has been found to cause
neuropathological disorders. Although the general toxicity of PM2. 5 has been intensively …

[HTML][HTML] A review of respirable fine particulate matter (PM2. 5)-induced brain damage

W Li, G Lin, Z Xiao, Y Zhang, B Li, Y Zhou… - Frontiers in Molecular …, 2022 - frontiersin.org
Respirable fine particulate matter (PM2. 5) has been one of the most widely publicied
indicators of pollution in recent years. Epidemiological studies have established a strong …

The impact of air pollution on neurodegenerative diseases

J Wang, T Ma, D Ma, H Li, L Hua, Q He… - Therapeutic Drug …, 2021 - journals.lww.com
Background: With the development of industrialization in human society, ambient pollutants
are becoming more harmful to human health. Epidemiological and toxicological studies …

Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model

SH Lee, YH Chen, CC Chien, YH Yan, HC Chen… - PLoS …, 2021 - journals.plos.org
Although numerous epidemiological studies revealed an association between ambient fine
particulate matter (PM2. 5) exposure and Alzheimer's disease (AD), the PM2. 5-induced …

Ambient PM2. 5 chronic exposure leads to cognitive decline in mice: From pulmonary to neuronal inflammation

Y Shou, X Zhu, D Zhu, H Yin, Y Shi, M Chen, L Lu… - Toxicology letters, 2020 - Elsevier
Abstract Fine particulate matter 2.5 (PM 2.5), one of the main components of air pollutants,
seriously threatens human health. Possible neuronal dysfunction induced by PM 2.5 has …

Microglial activation and inflammation caused by traffic-related particulate matter

KJ Bai, KJ Chuang, CL Chen, MK Jhan… - Chemico-biological …, 2019 - Elsevier
Neurotoxicity caused by particulate matter (PM) has been highlighted as being a potential
risk factor for neurodegenerative diseases. However, the effects of brain inflammation in …

PM2. 5 exposure in association with AD-related neuropathology and cognitive outcomes

K Thiankhaw, N Chattipakorn, SC Chattipakorn - Environmental Pollution, 2022 - Elsevier
Particulate matter with a diameter of less than 2.5 μm or PM2. 5 is recognized worldwide as
a cause of public health problems, mainly associated with respiratory and cardiovascular …

PM2. 5 exposure aggravates oligomeric amyloid beta-induced neuronal injury and promotes NLRP3 inflammasome activation in an in vitro model of Alzheimer's …

BR Wang, JQ Shi, NN Ge, Z Ou, YY Tian… - Journal of …, 2018 - Springer
Background Numerous studies suggested that PM2. 5 exposure was associated with
increased risk of Alzheimer's disease (AD). But the precise mechanisms by which PM2. 5 …

Particulate matter induced enhancement of inflammatory markers in the brains of apolipoprotein E knockout mice

A Campbell, JA Araujo, H Li, C Sioutas… - … of nanoscience and …, 2009 - ingentaconnect.com
Exposure to air particulate matter (PM) present in urban environments have been shown to
induce systemic prooxidant and proinflammatory effects in apolipoprotein E knockout (ApoE …