[HTML][HTML] G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide
G-quadruplexes are non-canonical nucleic-acid structures that control transcription,
replication, and recombination in organisms. G-quadruplexes are present in eukaryotes …
replication, and recombination in organisms. G-quadruplexes are present in eukaryotes …
[HTML][HTML] Analyses of viral genomes for G-quadruplex forming sequences reveal their correlation with the type of infection
G-quadruplexes contribute to the regulation of key molecular processes. Their utilization for
antiviral therapy is an emerging field of contemporary research. Here we present …
antiviral therapy is an emerging field of contemporary research. Here we present …
Viral G-quadruplexes: New frontiers in virus pathogenesis and antiviral therapy
E Ruggiero, SN Richter - Annual reports in medicinal chemistry, 2020 - Elsevier
Viruses are the most abundant organisms on our planet, affecting all living beings: some of
them are responsible for massive epidemics that concern health, national economies and …
them are responsible for massive epidemics that concern health, national economies and …
[HTML][HTML] G-Quadruplexes in the archaea domain
The importance of unusual DNA structures in the regulation of basic cellular processes is an
emerging field of research. Amongst local non-B DNA structures, G-quadruplexes (G4s) …
emerging field of research. Amongst local non-B DNA structures, G-quadruplexes (G4s) …
[HTML][HTML] G-quadruplexes involving both strands of genomic DNA are highly abundant and colocalize with functional sites in the human genome
AS Kudlicki - PLoS One, 2016 - journals.plos.org
The G-quadruplex is a non-canonical DNA structure biologically significant in DNA
replication, transcription and telomere stability. To date, only G4s with all guanines …
replication, transcription and telomere stability. To date, only G4s with all guanines …
G-quadruplexes in viruses: function and potential therapeutic applications
M Métifiot, S Amrane, S Litvak… - Nucleic acids …, 2014 - academic.oup.com
G-rich nucleic acids can form non-canonical G-quadruplex structures (G4s) in which four
guanines fold in a planar arrangement through Hoogsteen hydrogen bonds. Although many …
guanines fold in a planar arrangement through Hoogsteen hydrogen bonds. Although many …
[HTML][HTML] G-quadruplexes in pathogens: a common route to virulence control?
LM Harris, CJ Merrick - PLoS pathogens, 2015 - journals.plos.org
DNA can form several secondary structures besides the classic double helix: one that has
received much attention in recent years is the G-quadruplex (G4). This is a stable four …
received much attention in recent years is the G-quadruplex (G4). This is a stable four …
The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand
Guanine-rich nucleic acids can fold into G-quadruplexes, secondary structures implicated in
important regulatory functions at the genomic level in humans, prokaryotes and viruses. The …
important regulatory functions at the genomic level in humans, prokaryotes and viruses. The …
[HTML][HTML] The presence and localization of G-quadruplex forming sequences in the domain of bacteria
The role of local DNA structures in the regulation of basic cellular processes is an emerging
field of research. Amongst local non-B DNA structures, the significance of G-quadruplexes …
field of research. Amongst local non-B DNA structures, the significance of G-quadruplexes …
[HTML][HTML] QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs
Background Nucleic acids containing guanine tracts can form quadruplex structures via non-
Watson-Crick base pairing. Formation of G-quadruplexes is associated with the regulation of …
Watson-Crick base pairing. Formation of G-quadruplexes is associated with the regulation of …