Targeted ultrasound contrast agents for ultrasound molecular imaging and therapy

T van Rooij, V Daeichin, I Skachkov… - International journal …, 2015 - Taylor & Francis
Ultrasound contrast agents (UCAs) are used routinely in the clinic to enhance contrast in
ultrasonography. More recently, UCAs have been functionalised by conjugating ligands to …

Advancement of targeted ultrasound contrast agents and their applications in molecular imaging and targeted therapy

F Yang, ZY Chen, Y Lin - Current pharmaceutical design, 2013 - ingentaconnect.com
In recent years, targeted ultrasound contrast agents (UCA) have emerged with the rapid
development of contrast-enhanced ultrasound technology and bio-nanotechnology …

Nanosized contrast agents in ultrasound molecular imaging

F Zeng, M Du, Z Chen - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Applying nanosized ultrasound contrast agents (nUCAs) in molecular imaging has received
considerable attention. nUCAs have been instrumental in ultrasound molecular imaging to …

Multifunctional ultrasound contrast agents for imaging guided photothermal therapy

C Guo, Y Jin, Z Dai - Bioconjugate Chemistry, 2014 - ACS Publications
Among all the imaging techniques, ultrasound imaging has a unique advantage due to its
features of real-time, low cost, high safety, and portability. Ultrasound contrast agents …

Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery

V Paefgen, D Doleschel, F Kiessling - Frontiers in pharmacology, 2015 - frontiersin.org
Ultrasound (US) is one of the most frequently used diagnostic methods. It is a non-invasive,
comparably inexpensive imaging method with a broad spectrum of applications, which can …

Molecular ultrasound imaging: current status and future directions

N Deshpande, A Needles, JK Willmann - Clinical radiology, 2010 - Elsevier
Targeted contrast-enhanced ultrasound (molecular ultrasound) is an emerging imaging
strategy that combines ultrasound technology with novel molecularly-targeted ultrasound …

Ultrasound contrast agents and delivery systems in cancer detection and therapy

R Perera, P Nittayacharn, M Cooley, O Jung… - Advances in Cancer …, 2018 - Elsevier
Ultrasound is the second most utilized imaging modality in the world because it is widely
accessible, robust, and safe. Aside from its extensive use in diagnostic imaging, ultrasound …

Molecular imaging agents for ultrasound

A Zlitni, SS Gambhir - Current opinion in chemical biology, 2018 - Elsevier
Highlights•First in human trials show promise in the utility of molecular US imaging in
identifying malignant from benign lesions.•Nanometer sized bubbles which can extravasate …

Ultrasound technology for molecular imaging: from contrast agents to multimodal imaging

Y Li, Y Chen, M Du, ZY Chen - ACS Biomaterials Science & …, 2018 - ACS Publications
Ultrasound (US) takes advantage of ultrasound contrast agents (UCAs) to further increase
the sensitivity and specificity of monitoring at the cellular level, which has had a …

Multimodal micro, nano, and size conversion ultrasound agents for imaging and therapy

E Huynh, MA Rajora, G Zheng - Wiley Interdisciplinary Reviews …, 2016 - Wiley Online Library
Ultrasound (US) is one of the most commonly used clinical imaging techniques. However,
the use of US and US‐based intravenous agents extends far beyond imaging. In particular …