[HTML][HTML] Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

[HTML][HTML] Hepatitis C virus molecular evolution: transmission, disease progression and antiviral therapy

MV Preciado, P Valva, A Escobar-Gutierrez… - World journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection represents an important public health problem worldwide.
Reduction of HCV morbidity and mortality is a current challenge owned to several viral and …

Current and future therapies for hepatitis C virus infection

TJ Liang, MG Ghany - New England Journal of Medicine, 2013 - Mass Medical Soc
Current and Future Therapies for Hepatitis C Virus Infection | New England Journal of Medicine
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The face of future hepatitis C antiviral drug development: recent biological and virologic advances and their translation to drug development and clinical practice

JG McHutchison, R Bartenschlager, K Patel… - Journal of …, 2006 - Elsevier
The face of future hepatitis C antiviral drug development: Recent biological and virologic
advances and their translation to drug development and clinical practice - ScienceDirect Skip …

[PDF][PDF] Therapy of hepatitis C: from empiricism to eradication

JM Pawlotsky - Hepatology, 2006 - Wiley Online Library
The complications of chronic hepatitis C virus infection can be prevented by antiviral
therapy. The initial choice of interferon alfa and, subsequently, ribavirin as potential …

[HTML][HTML] New hepatitis C virus (HCV) drugs and the hope for a cure: concepts in anti-HCV drug development

JM Pawlotsky - Seminars in liver disease, 2014 - thieme-connect.com
The development of new models and tools has led to the discovery and clinical development
of a large number of new anti-hepatitis C virus (HCV) drugs, including direct-acting antivirals …

Novel therapies for hepatitis C—one pill fits all?

MP Manns, T Von Hahn - Nature reviews Drug discovery, 2013 - nature.com
Almost 25 years after the hepatitis C virus (HCV) was identified, and following intense
research and development efforts, a large number of direct-acting antiviral drugs are now …

[PDF][PDF] Hepatitis C. Development of new drugs and clinical trials: promises and pitfalls. Summary of an AASLD hepatitis single topic conference, Chicago, IL, February …

JM Pawlotsky, JG McHutchison - Hepatology, 2004 - Wiley Online Library
Chronic hepatitis C virus (HCV) infection affects a large number of patients worldwide. While
our current therapies (Table 1) are effective in approximately 50% of patients, therapy is …

Challenges and successes in developing new therapies for hepatitis C

R De Francesco, G Migliaccio - Nature, 2005 - nature.com
Hepatitis C virus (HCV) will continue to be a serious global health threat for many years to
come because of the chronic nature of the infection, its high prevalence and the significant …

[HTML][HTML] Hepatitis C in a new era: a review of current therapies

T Kish, A Aziz, M Sorio - Pharmacy and Therapeutics, 2017 - ncbi.nlm.nih.gov
Hepatitis C in a New Era: A Review of Current Therapies - PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …