IgG antiphospholipid antibodies (aPL) exert direct effects on various cell types, contributing
to the pathogenesis of thrombosis and pregnancy morbidity in patients with the …

The antiphospholipid syndrome (APS) refers to persistent antiphospholipid antibodies (aPL)
associated with thrombotic and/or obstetrical complications. The endothelial cell is a target …

in microparticle production. Microparticles can influence the development of thrombosis in
many ways. For example, microparticles provide a catalytic surface for the assembly of …

Antiphospholipid syndrome is an autoimmune disease characterized by the persistent
presence of antiphospholipid antibodies, along with occurrence of vascular thrombosis and …

Background The antiphospholipid syndrome (APS) is the association of thrombosis and
recurrent pregnancy loss and/or pregnancy morbidity with persistent antiphospholipid …

Antiphospholipid antibodies (aPL), particularly those directed against β 2-glycoprotein I,
cause activation of vascular cells (endothelial cells, platelets, monocytes) and release of …

Vascular dysfunction is key to the development of thrombosis in the antiphospholipid
syndrome. This has been largely demonstrated by the upregulation of various cell surface …

The antiphospholipid syndrome is characterized by venous or arterial thrombosis and/or
recurrent fetal loss in the presence of circulating antiphospholipid antibodies. These …

Antiphospholipid (aPL) antibodies, detected in patients with antiphospholipid syndrome
(APS) are associated with thrombosis, pregnancy loss and thrombocytopenia. Studies have …

Antiphospholipid syndrome (APS) is an autoimmune disease driven by a wide group of
autoantibodies primarily directed against phospholipid-binding proteins (antiphospholipid …