Genome duplication is essential for cell proliferation and DNA synthesis is generally initiated
by dedicated replication proteins at specific loci termed origins. During DNA replication …

Genome duplication is essential for the proliferation of cellular life and this process is
generally initiated by dedicated replication proteins at chromosome origins. In bacteria, DNA …

Genome duplication is essential for cell proliferation, and DNA synthesis is generally
initiated by dedicated replication proteins at specific loci termed origins. In bacteria, the …

Genome replication is a fundamental biological activity shared by all organisms.
Chromosomal replication proceeds bidirectionally from origins, requiring the loading of two …

Genome replication is a fundamental requirement for the proliferation of all cells. Throughout
the domains of life, conserved DNA replication initiation proteins assemble at specific …

The homotetrameric DnaD protein is essential in low G+ C content gram positive bacteria
and is involved in replication initiation at oriC and re-start of collapsed replication forks. It …

Bacterial chromosome replication is initiated by binding of DnaA to a DnaA-box cluster
(DBC) within the replication origin (oriC). In Bacillus subtilis, six additional DBCs are found …

Bidirectional DNA replication from a chromosome origin requires the asymmetric loading of
two helicases, one for each replisome. Our understanding of the molecular mechanisms …

Although division site positioning in rod‐shaped bacteria is generally believed to occur
through the combined effect of nucleoid occlusion and the Min system, several lines of …

The mechanisms responsible for helicase loading during the initiation of chromosome
replication in bacteria are unclear. Here we report both a positive and a negative …