Fertility preservation is an important type of frontier scientific research in the field of
reproductive health. The culture of ovarian cortices to i) initiate primordial follicle growth and …

Fertility preservation is an important type of frontier scientific research in the field of
reproductive health. The culture of ovarian cortices to i) initiate primordial follicle growth and …

The recruitment of primordial follicles to initiate folliculogenesis determines the population of
developing follicles available for ovulation and directly regulates female reproductive …

BACKGROUND In vitro follicle growth is a promising fertility preservation strategy in which
ovarian follicles are cultured to produce mature and fertilization-competent oocytes …

STUDY QUESTION What is the effect of basic fibroblast growth factor (bFGF) on the growth
of individual early human follicles in a three-dimensional (3D) culture system in vitro …

Primordial follicle assembly is a process that occurs when oocyte nests break down to form
individual primordial follicles. The size of this initial pool of primordial follicles in part …

Dormant primordial follicles (PFs) are the most abundant reproductive resource in
mammalian ovaries. With advances in the mechanism of study of the regulation of PF …

OBJECTIVE: To evaluate whether basic fibroblast growth factor (FGF) benefits the in vitro
development of human primordial follicles. DESIGN: Human ovarian tissue was placed in …

We performed an immunohistochemical (IHC) study to determine the follicular expression of
growth differentiation factor 9 (GDF-9), anti-Müllerian hormone (AMH), Kit Ligand (KL), and c …

In the mammalian ovaries, dormant primordial follicles represent the reproductive reserve of
individual females. Recently, stimulating the activation of primordial follicles in vitro has …