Viral gastroenteritis

K Bányai, MK Estes, V Martella, UD Parashar - The Lancet, 2018 - thelancet.com
Enteric viruses, particularly rotaviruses and noroviruses, are a leading cause of
gastroenteritis worldwide. Rotaviruses primarily affect young children, accounting for almost …

Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant

B Lopman, H Vennema, E Kohli, P Pothier, A Sanchez… - The lancet, 2004 - thelancet.com
Background Highly publicised outbreaks of norovirus gastroenteritis in hospitals in the UK
and Ireland and cruise ships in the USA sparked speculation about whether this reported …

Epidemiology of human noroviruses and updates on vaccine development

S Ramani, RL Atmar, MK Estes - Current opinion in …, 2014 - journals.lww.com
The importance of NoVs as a major gastrointestinal pathogen underscores the need for well
tolerated and effective vaccines. Results of VLP vaccine trials appear promising. However …

Norovirus vaccines: current clinical development and challenges

M Tan - Pathogens, 2021 - mdpi.com
Noroviruses are the major viral pathogens causing epidemic and endemic acute
gastroenteritis with significant morbidity and mortality. While vaccines against norovirus …

Norovirus gastroenteritis

RI Glass, UD Parashar, MK Estes - New England Journal of …, 2009 - Mass Medical Soc
Noroviruses are now recognized as the leading cause of epidemics of gastroenteritis and an
important cause of sporadic gastroenteritis among both children and adults. In the United …

Recent advances in human norovirus research and implications for candidate vaccines

JE Cates, J Vinjé, U Parashar, AJ Hall - Expert review of vaccines, 2020 - Taylor & Francis
Introduction Noroviruses are a leading cause of acute gastroenteritis worldwide. An
estimated 21 million illnesses in the United States and upwards of 684 million illnesses …

Norovirus vaccine against experimental human GII. 4 virus illness: a challenge study in healthy adults

DI Bernstein, RL Atmar, GM Lyon… - The Journal of …, 2015 - academic.oup.com
Background. Vaccines against norovirus, the leading cause of acute gastroenteritis, should
protect against medically significant illness and reduce transmission. Methods. In this …

The state of norovirus vaccines

K Debbink, LC Lindesmith… - Clinical Infectious Diseases, 2014 - academic.oup.com
While there is currently no approved norovirus vaccine, recent human clinical efficacy trials
with virus-like particle–based vaccines have shown promise. Several additional norovirus …

Norovirus gastroenteritis in immunocompromised patients

K Bok, KY Green - New England Journal of Medicine, 2012 - Mass Medical Soc
Norovirus Gastroenteritis in Immunocompromised Patients | New England Journal of Medicine
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The vast and varied global burden of norovirus: prospects for prevention and control

BA Lopman, D Steele, CD Kirkwood… - PLoS medicine, 2016 - journals.plos.org
Globally, norovirus is associated with approximately one-fifth of all diarrhea cases, with
similar prevalence in both children and adults, and is estimated to cause over 200,000 …