Background Detoxification is frequently recommended as a treatment for moderate to severe
Cocaine Use Disorder (CUD). However, the response to detoxification varies among …

Abstract Background and Objectives Cocaine is a highly addictive substance, and with no
approved medication for cocaine use disorder (CUD), leading to a heavy burden. Despite …

Background: Cocaine dependents are a highly heterogeneous population. An appropriate
system of classification should represent a broad understanding of underlying psychosocial …

Preclinical and clinical studies suggest that individual drug withdrawal symptoms may have
differential effects on addictive behaviors. The goals of this study were (1) to explore the …

Background Anecdotal evidence suggests a substantial proportion of individuals with
cocaine use disorder do not report craving during inpatient detoxification. Objective To …

Background: The effects of cannabis on clinical outcomes of treatment services for other
drug use disorders remains unclear. The primary aim of the current study was to investigate …

Background The severity of substance use disorder (SUD) is currently defined by the sum of
DSM-5 criteria. However, little is known about the validity of this framework or the role of …

The relations among psychiatric and substance dependence disorders and treatment
utilization are of clinical interest both for their clinical management and for health services …

The current study assessed demographic, drug and psychiatric predictors of dropout in the
pilot/training phase of a large, multi-site psychotherapy outcome study for patients with …

Both cocaine withdrawal symptoms, measured by an instrument called the Cocaine
Selective Severity Assessment (CSSA), and urine toxicology results obtained at the start of …