Early, intensive, lower extremity rehabilitation shows preliminary efficacy after perinatal stroke: results of a pilot randomized controlled trial

C Hurd, D Livingstone, K Brunton… - … and Neural Repair, 2022 - journals.sagepub.com
Background Perinatal stroke injures motor regions of the brain, compromising movement for
life. Early, intensive, active interventions for the upper extremity are efficacious, but …

Early intensive leg training to enhance walking in children with perinatal stroke: protocol for a randomized controlled trial

C Hurd, D Livingstone, K Brunton, M Teves… - Physical …, 2017 - academic.oup.com
Background. Development of motor pathways is modulated by activity in these pathways,
when they are maturing (ie, critical period). Perinatal stroke injures motor pathways …

Intervention-induced motor cortex plasticity in hemiparetic children with perinatal stroke

HC Kuo, E Zewdie, P Ciechanski… - … and Neural Repair, 2018 - journals.sagepub.com
Background. Clinical trials are suggesting efficacy of intensive therapy combined with brain
stimulation to improve hand function in hemiparetic children with perinatal stroke. However …

Early intervention after perinatal stroke: opportunities and challenges

AP Basu - Developmental Medicine & Child Neurology, 2014 - Wiley Online Library
Perinatal stroke is the most common cause of hemiplegic cerebral palsy. No standardized
early intervention exists despite evidence for a critical time window for activity‐dependent …

Feasibility trial of an early therapy in perinatal stroke (eTIPS)

AP Basu, J Pearse, R Watson, P Dulson, J Baggaley… - BMC neurology, 2018 - Springer
Background Perinatal stroke (PS) affects up to 1/2300 infants and frequently leads to
unilateral cerebral palsy (UCP). Preterm-born infants affected by unilateral haemorrhagic …

Current therapeutic management of perinatal stroke with a focus on the upper limb: A cross-sectional survey of UK physiotherapists and occupational therapists

C Marcroft, A Tsutsumi, J Pearse, P Dulson… - … therapy in pediatrics, 2019 - Taylor & Francis
Aim: To determine current UK pediatric physiotherapist (PT) and occupational therapist (OT)
management of perinatal stroke. Design: Web-based cross-sectional survey. Methods …

Participatory design in the development of an early therapy intervention for perinatal stroke

AP Basu, JE Pearse, J Baggaley, RM Watson, T Rapley - BMC pediatrics, 2017 - Springer
Background Perinatal stroke is the leading cause of unilateral (hemiparetic) cerebral palsy,
with life-long personal, social and financial consequences. Translational research findings …

Perinatal stroke: mapping and modulating developmental plasticity

A Kirton, MJ Metzler, BT Craig, A Hilderley… - Nature Reviews …, 2021 - nature.com
Most cases of hemiparetic cerebral palsy are caused by perinatal stroke, resulting in lifelong
disability for millions of people. However, our understanding of how the motor system …

Brain stimulation and constraint for hemiparesis after perinatal stroke: The PLASTIC CHAMPS trial

A Kirton, J Andersen, M Herrero, L Carsolio… - Canadian Journal of …, 2015 - cambridge.org
Background: Perinatal stroke causes hemiparetic cerebral palsy. Constraint therapy (CIMT)
improves function in congenital hemiparesis and adult stroke. Repetitive transcranial …

Perspectives of parents partnering with physical therapists to deliver intensive rehabilitation for their young children with perinatal stroke: A qualitative study

CL Hurd, L Pritchard, JF Yang - Child: Care, Health and …, 2024 - Wiley Online Library
Background Parental participation in their young children's rehabilitation has been promoted
to increase intervention intensity, but parents' perspectives on increased involvement remain …