An epigenetic mechanism for differential maturation of amygdala–prefrontal connectivity in childhood socio-emotional development

AM Skyberg, BT Newman, AJ Graves… - Translational …, 2023 - nature.com
Functional connectivity between the amygdala and the medial prefrontal cortex (mPFC) has
been identified as a neural substrate of emotion regulation that undergoes changes …

Decreased amygdala–insula resting state connectivity in behaviorally and emotionally dysregulated youth

G Bebko, M Bertocci, H Chase, A Dwojak… - Psychiatry Research …, 2015 - Elsevier
Abstract The Research Domain Criteria (RDoC) adopts a dimensional approach for
examining pathophysiological processes underlying categorically defined psychiatric …

[HTML][HTML] Distinctive heritability patterns of subcortical-prefrontal cortex resting state connectivity in childhood: A twin study

M Achterberg, MJ Bakermans-Kranenburg… - Neuroimage, 2018 - Elsevier
Connectivity between limbic/subcortical and prefrontal-cortical brain regions develops
considerably across childhood, but less is known about the heritability of these networks at …

Development of amygdala functional connectivity during infancy and its relationship with 4-year behavioral outcomes

AP Salzwedel, RL Stephens, BD Goldman… - Biological Psychiatry …, 2019 - Elsevier
Background The amygdala represents a core node in the human brain's emotional signal
processing circuitry. Given its critical role, both the typical and atypical functional connectivity …

Developmental pathways to amygdala-prefrontal function and internalizing symptoms in adolescence

CA Burghy, DE Stodola, PL Ruttle, EK Molloy… - Nature …, 2012 - nature.com
Early life stress (ELS) and function of the hypothalamic-pituitary-adrenal axis predict later
psychopathology. Animal studies and cross-sectional human studies suggest that this …

Maternal cortisol is associated with neonatal amygdala microstructure and connectivity in a sexually dimorphic manner

DQ Stoye, M Blesa, G Sullivan, P Galdi, GJ Lamb… - Elife, 2020 - elifesciences.org
The mechanisms linking maternal stress in pregnancy with infant neurodevelopment in a
sexually dimorphic manner are poorly understood. We tested the hypothesis that maternal …

Reduced fronto-amygdalar connectivity in adolescence is associated with increased depression symptoms over time

H Scheuer, G Alarcón, DV Demeter, E Earl… - Psychiatry Research …, 2017 - Elsevier
Depression is common among adolescents, affecting greater than 12% of youth in a given
year. Studies have shown aberrant amygdala connectivity in depressed adolescents …

Amygdala functional connectivity is associated with emotion regulation and amygdala reactivity in 4-to 6-year-olds

MS Gaffrey, DM Barch, JL Luby, SE Petersen - Journal of the American …, 2021 - Elsevier
Objective Emotion dysregulation has been suggested to be a potent risk factor for multiple
psychiatric conditions. Altered amygdala− prefrontal cortex (PFC) connectivity has been …

Amygdala–medial prefrontal cortex connectivity relates to stress and mental health in early childhood

AT Park, JA Leonard, PK Saxler, AB Cyr… - Social Cognitive and …, 2018 - academic.oup.com
Early life stress has been associated with disrupted functional connectivity between the
amygdala and medial prefrontal cortex (mPFC), but it is unknown how early in development …

[HTML][HTML] Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants

KL Humphreys, MC Camacho, MC Roth… - Developmental cognitive …, 2020 - Elsevier
Stressful experiences are linked to neurodevelopment. There is growing interest in the role
of stress in the connectivity between the amygdala and medial prefrontal cortex (mPFC), a …