Current nucleic acid extraction methods and their implications to point‐of‐care diagnostics

N Ali, RCP Rampazzo, ADT Costa… - BioMed research …, 2017 - Wiley Online Library
Nucleic acid extraction (NAE) plays a vital role in molecular biology as the primary step for
many downstream applications. Many modifications have been introduced to the original …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Sample preparation: a challenge in the development of point-of-care nucleic acid-based assays for resource-limited settings

MA Dineva, L Mahilum-Tapay, H Lee - Analyst, 2007 - pubs.rsc.org
Currently available nucleic acid testing (NAT)-based assays are complex and time-
consuming, and they require expensive instrumentation and dedicated laboratory spaces for …

[HTML][HTML] Low concentration DNA extraction and recovery using a silica solid phase

C Katevatis, A Fan, CM Klapperich - PloS one, 2017 - journals.plos.org
DNA extraction from clinical samples is commonly achieved with a silica solid phase
extraction column in the presence of a chaotrope. Versions of these protocols have been …

PCR technologies for point of care testing: progress and perspectives

S Petralia, S Conoci - ACS sensors, 2017 - ACS Publications
Since the Human Genome Project completed in 2000, the sequencing of the first genome,
massive progress has been made by medical science in the early diagnosis and …

[PDF][PDF] The evolution of DNA extraction methods

M Dairawan, PJ Shetty - Am. J. Biomed. Sci. Res, 2020 - pdfs.semanticscholar.org
Since the first DNA extraction performed by Friedrich Miescher in 1869, scientists have
made extraordinary progress in designing extraction methods that are more reliable, easier …

Nucleic acid extraction: fundamentals of sample preparation methodologies, current advancements, and future endeavors

MN Emaus, M Varona, DR Eitzmann, SA Hsieh… - TrAC Trends in …, 2020 - Elsevier
The extraction of nucleic acids (NA) is an essential component of NA analysis. Without
sufficient extraction and purification, contaminants co-existing with NAs often inhibit …

Point-of-care nucleic acid detection using nanotechnology

MR Hartman, RCH Ruiz, S Hamada, C Xu, KG Yancey… - Nanoscale, 2013 - pubs.rsc.org
Recent developments in nanotechnology have led to significant advancements in point-of-
care (POC) nucleic acid detection. The ability to sense DNA and RNA in a portable format …

Integrated point-of-care molecular diagnostic devices for infectious diseases

W Liu, F Yue, LP Lee - Accounts of chemical research, 2021 - ACS Publications
Conspectus The global outbreaks of deadly infectious diseases caused by pathogenic
microorganisms have threatened public health worldwide and significantly motivated …

[HTML][HTML] DNA, RNA, and protein extraction: the past and the present

SC Tan, BC Yiap - BioMed research international, 2009 - Wiley Online Library
Extraction of DNA, RNA, and protein is the basic method used in molecular biology. These
biomolecules can be isolated from any biological material for subsequent downstream …