Background Neuroinflammation-induced injury is intimately associated with poor prognosis
in patients with cerebral venous sinus thrombosis (CVST). The cyclic GMP-AMP synthase …

Background Ischaemia-evoked neuroinflammation is a critical pathogenic event following
ischaemic stroke. Gasdermin D (GSDMD)-associated pyroptosis represents a type of …

Stimulator of interferons genes (STING), which is crucial for the secretion of type I interferons
and proinflammatory cytokines in response to cytosolic nucleic acids, plays a key role in the …

Inflammation plays a pivotal role in promoting the pathophysiology of ischemic stroke (IS).
Microglia is the major immunocompetent cells involved in different neuropathologies. The …

Neuroinflammation driven by type-I interferons in the CNS is well established to exacerbate
the progression of many CNS pathologies both acute and chronic. The role of adaptor …

Neuroinflammation is initiated in response to ischemic stroke, and is usually characterized
by microglial activation and polarization. Stimulator of interferon genes (STING) has been …

The cyclic guanosine monophosphate–adenosine monophosphate (GMP‐AMP) synthase‐
Stimulator of Interferon Genes (cGAS‐STING) pathway is a critical innate immune …

Long‐term neurological deficits after severe traumatic brain injury (TBI), including cognitive
dysfunction and emotional impairments, can significantly impair rehabilitation. Glial …

Background Neuroinflammation is closely associated with the poor prognosis in
subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of …

Background Traumatic brain injury (TBI) represents a major cause of disability and death
worldwide with sustained neuroinflammation and autophagy dysfunction contributing to the …