The specific neural systems underlying the subjective feeling of fear are debated in affective
neuroscience. Here, we combine functional MRI with machine learning to identify and …

In studies of anxiety and other affective disorders, objectively measured physiological
responses have commonly been used as a proxy for measuring subjective experiences …

Uncertainty about potential future threats and the associated anxious anticipation represents
a key feature of anxiety. However, the neural systems that underlie the subjective …

While much research has elucidated the neurobiology of fear learning, the neural systems
supporting the generalization of learned fear are unknown. Using functional magnetic …

Aversive events are typically more debilitating when they occur unpredictably than
predictably. Studies in humans and animals indicate that predictable and unpredictable …

Exploring the neural circuits of the extinction of conditioned fear is critical to advance our
understanding of fear-and anxiety-related disorders. The field has focused on examining the …

Functionally, anxiety serves to increase vigilance towards aversive stimuli and improve the
ability to detect and avoid danger. We have recently shown, for instance, that anxiety …

Effective perception of fear signals is crucial for human survival and the importance of the
amygdala in this process is well documented. Animal, lesion and neuroimaging studies …

Anxiety is one of the most common mental states of humans. Although it drives us to avoid
frightening situations and to achieve our goals, it may also impose significant suffering and …

The tremendous variability within categories of human emotional experience receives little
empirical attention. We hypothesized that atypical instances of emotion categories (eg …