Objective Selecting interventions for patients with solitary hepatocellular carcinoma (HCC)
remains a challenge. Despite gross classification being proposed as a potential prognostic …

Aim The clinical impact of pathological classification based on architectural pattern in
hepatocellular carcinoma (HCC) remains elusive in spite of its well-known and common …

Background While resection is a recommended treatment for patients with stage 1
hepatocellular carcinoma (HCC), it remains controversial for multifocal disease. We sought …

Background Liver resection is currently the only recommended treatment option for solitary
hepatocellular carcinoma (HCC) at an early stage, with well‐preserved liver function and no …

Background A solitary hepatocellular carcinoma (HCC) without macrovascular invasion and
distant metastasis, regardless of tumor size, is currently classified as early-stage disease by …

Background According to the 7th AJCC TNM staging system, solitary hepatocellular
carcinoma (HCC) is classified as T1 or T2 based on microvascular invasion (MVI) regardless …

Solitary large hepatocellular carcinoma (SLHCC) is a specific subtype of HCC with unique
characteristics. It is of great interest to assess and stratify the prognosis of SLHCCs after …

Staging systems are key to predict the prognosis of patients with cancer, to stratify the
patients according to prognostic variables in the setting of clinical trials, to allow the …

Background & Aims Our increasing understanding of hepatocellular carcinoma (HCC)
biology holds promise for personalized care, however its translation into clinical practice …

Abstract Purpose The current American Joint Committee on Cancer (AJCC) staging system
for hepatocellular carcinoma (HCC) includes all solitary tumors without vascular invasion as …