Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

[HTML][HTML] The role of short-chain fatty acids from gut microbiota in gut-brain communication

YP Silva, A Bernardi, RL Frozza - Frontiers in endocrinology, 2020 - frontiersin.org
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the
regulation of metabolic, endocrine and immune functions. In recent years, there has been …

The role of short-chain fatty acids in microbiota–gut–brain communication

B Dalile, L Van Oudenhove, B Vervliet… - Nature reviews …, 2019 - nature.com
Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of
dietary fibre in the gastrointestinal tract, are speculated to have a key role in microbiota–gut …

[HTML][HTML] Gut-brain axis: Focus on gut metabolites short-chain fatty acids

C Guo, YJ Huo, Y Li, Y Han, D Zhou - World journal of clinical …, 2022 - ncbi.nlm.nih.gov
Emerging evidence supports that the gut microbiome, reconsidered as a new organ in the
human body, can not only affect the local gut, but also communicate with the brain via …

Short‐chain fatty acids: microbial metabolites that alleviate stress‐induced brain–gut axis alterations

M Van de Wouw, M Boehme, JM Lyte… - The Journal of …, 2018 - Wiley Online Library
Key points Chronic (psychosocial) stress changes gut microbiota composition, as well as
inducing behavioural and physiological deficits. The microbial metabolites short‐chain fatty …

Short-chain fatty acids in the microbiota–gut–brain axis: role in neurodegenerative disorders and viral infections

A Majumdar, IP Siva Venkatesh… - ACS Chemical …, 2023 - ACS Publications
The gut–brain axis (GBA) is the umbrella term to include all bidirectional communication
between the brain and gastrointestinal (GI) tract in the mammalian body. Evidence from over …

From gut microbiota dysfunction to obesity: could short-chain fatty acids stop this dangerous course?

L Barrea, G Muscogiuri, G Annunziata, D Laudisio… - Hormones, 2019 - Springer
Study of the interactions between the gut microbiota and brain-gut axis represents a very
appealing approach to increasing our knowledge about the mechanisms leading to obesity …

Small talk: microbial metabolites involved in the signaling from microbiota to brain

G Caspani, J Swann - Current opinion in pharmacology, 2019 - Elsevier
The wealth of biotransformational capabilities encoded in the microbiome expose the host to
an array of bioactive xenobiotic products. Several of these metabolites participate in the …

Short-chain fatty acids-producing probiotics: A novel source of psychobiotics

Y Cheng, J Liu, Z Ling - Critical reviews in food science and …, 2022 - Taylor & Francis
Psychobiotics—live microorganisms with potential mental health benefits, which can
modulate the microbiota-gut-brain-axis via immune, humoral, neural, and metabolic …

Central and peripheral regulations mediated by short-chain fatty acids on energy homeostasis

P Luo, K Lednovich, K Xu, C Nnyamah, BT Layden… - Translational …, 2022 - Elsevier
The human gut microbiota influences obesity, insulin resistance, and the subsequent
development of type 2 diabetes (T2D). The gut microbiota digests and ferments nutrients …